Clinical Rheumatology 1986-Dec
Colchicine suppression of local inflammation due to calcinosis in dermatomyositis and progressive systemic sclerosis.
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Abstrakt
Two girls, one with progressive systemic sclerosis and a second with dermatomyositis, developed calcinosis in the skin of the prepatellar area. Calcinosis was accompanied by local inflammation and skin ulceration. Oral colchicine therapy in a dosage of 1 mg per day was followed within two months by significant regression of local inflammation and healing of the skin ulcers.