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acetic acid/fedme
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.alpha.-amino-indole-3-acetic acids useful as anti-diabetic, anti-obesity and anti-atherosclerotic agents
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BACKGROUND OF THE INVENTION
The present invention provides novel compounds. More particularly, the present invention provides novel .alpha.-amino-indole-3-acetic acids, tryptophans and their derivatives. The compounds are useful as anti-diabetic, anti-obesity and anti-atherosclerotic
Indane acetic acid derivatives and their use as pharmaceutical agents
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FIELD OF THE INVENTION
This invention is directed to the use of indane acetic acid derivatives and pharmaceutical compositions useful in the treatment of disease such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in
Indole acetic acid derivatives and their use as pharmaceutical agents
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FIELD OF THE INVENTION
This invention is directed to indole acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation
Indole acetic acid derivatives and their use as pharmaceutical agents
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FIELD OF THE INVENTION
This invention is directed to indole acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation
Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
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FIELD OF THE INVENTION
This invention is directed to indane acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation
Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
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FIELD OF THE INVENTION
This invention is directed to indane acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation
Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
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FIELD OF THE INVENTION
This invention is directed to indane acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation
Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
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FIELD OF THE INVENTION
This invention is directed to indane acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation
Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
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This application claims benefit of U.S. Provisional Application Ser. No. 60/435,310, filed Dec. 20, 2002, the contents of which are incorporated herein by reference in their entirety.
FIELD OF THE INVENTION
This invention is directed to indane acetic acid derivatives and their use in pharmaceutical
Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
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FIELD OF THE INVENTION
This invention is directed to indane acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation
Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
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FIELD OF THE INVENTION
This invention is directed to indane acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation
Phenoxy acetic acids and phenyl propionic acids as PPAR.delta. agonists
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FIELD OF THE INVENTION
The present invention relates to novel compounds, to the use of these compounds as pharmaceutical compositions, to pharmaceutical compositions comprising the compounds and to a method of treatment employing these compounds and compositions. The compounds are activators of
Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists
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FIELD OF THE INVENTION
The present invention relates to novel compounds, to the use of these compounds as pharmaceutical compositions, to pharmaceutical compositions comprising the compounds and to a method of treatment employing these compounds and compositions. The compounds are activators of
Benzoazepin-oxy-acetic acid derivatives as PPAR-delta agonists used for the increase of HDL-C, lower LDL-C and lower cholesterol
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STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT
The research and development of the invention described below was not federally sponsored.
BACKGROUND OF THE INVENTION
The peroxisome proliferator-activated receptors (PPARs) are considered to be metabolic sensors regulating the
Benzoazepin-oxy-acetic acid derivatives as PPAR-delta agonists used for the increase of HDL-C, lower LDL-C and lower cholesterol
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STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT
The research and development of the invention described below was not federally sponsored.
BACKGROUND OF THE INVENTION
The peroxisome proliferator-activated receptors (PPARs) are considered to be metabolic sensors regulating the
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