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3 resultater
Toxicology and carcinogenesis studies of propargyl alcohol (CAS No. 107-19-7) in F344/N rats and B6C3F1 mice (inhalation studies).
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Propargyl alcohol is a commercially available acetylenic primary alcohol. It is also a by-product in the industrial synthesis of butynediol from acetylene and formaldehyde with copper acetylide as catalyst. Propargyl alcohol is used as a reactant/chemical intermediate, pharmaceutical intermediate,
Local treatment of cutaneous and subcutaneous metastatic malignant melanoma with fotemustine.
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Fotemustine is a highly reactive chloroethyl-nitrosourea anti-tumor drug that is currently undergoing phase III clinical trials in stage IV metastatic malignant melanoma. The drug is a potent alkylating agent and rapidly chloroethylates the active sites of the important thioproteins thioredoxin
Local transplant of human umbilical cord matrix stem cells improves skin flap survival in a mouse model.
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A skin flap is a piece of skin that has its own blood supply, which is useful to repair large skin defects and deep wounds in plastic surgery. However, partial skin flap necrosis usually occurred. Bone marrow mesenchymal stem cells (BM MSCs) are effective in improving the ischemic flap survival, but
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