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adriamycin/infarkt
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Side 1 fra 45 resultater
[Myocardial infarct after adriamycin].
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[Adriamycin, cisplatin and etoposide combination chemotherapy in non-small cell lung cancer].
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Nineteen patients with non-small cell lung cancer (eight patients with adenocarcinoma, nine patients with squamous cell carcinoma, one patient with large cell carcinoma and one patient with sarcoma) who had not received previous chemotherapy were treated with a combination of adriamycin (30 mg/m2,
Results of three courses of adriamycin, bleomycin, vindesine, and dacarbazine with subtotal nodal irradiation in 189 patients with nodal Hodgkin's disease (stage I, II and IIIA).
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OBJECTIVE
To evaluate in a prospective trial three courses of an ABVD-like chemotherapy (CT) regimen given before radiation therapy (RT) (subtotal nodal irradiation (STNI) in favorable stage Hodgkin's disease (HD). The efficacy, risk factors and medium-term toxicities are reported.
METHODS
Stage I
Staphylococcal endocarditis presenting with a renal infarct in a patient with acute lymphoblastic leukemia.
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We present here a patient with acute lymphoblastic leukemia (ALL) and who developed infective endocarditis during induction chemotherapy with prednisolone, L-asparaginase (Leunase), vincristine and adriamycin. The patient did not have a history of a central venous catheter. Sharp flank pain and
[Successful Treatment of Malignant Lymphoma Arising from the Left Atrial Myxoma with Acute Myocardial Infarction;Report of a Case].
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Primary cardiac malignant lymphoma within a cardiac myxoma is extremely rare. Here we report a case of a previously healthy 71-year-old woman who developed acute myocardial infarction. Transthoracic echocardiography showed a 69×45-mm solid tumor in the left atrium that was moving in a circular
Internal associations and dynamic expression of c-kit and nanog genes in ventricular remodelling induced by adriamycin.
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The present study aimed to investigate the dynamic expression of the c-kit and nanog genes in rats with left ventricular remodelling induced by adriamycin (ADR), and explore its internal association and mechanism of action. Sprague-Dawley male rats were randomly divided into a normal control group
Effect of L-carnitine supplementation on cardiac carnitine palmitoyltransferase activities and plasma carnitine concentrations in adriamycin-treated rats.
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Adriamycin (ADR) inhibits the carnitine palmitoyl transferase (CPT) system and consequently the transport of long-chain fatty acids across mitochondrial membranes. l-Carnitine (CARN) plays a major role in fatty acid oxidation by translocating activated long-chain fatty acids into the matrix of
Sequential Adriamycin and CMF in Metastatic Breast Cancer.
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PURPOSE: To evaluate the clinical activity of a sequential treatment with Adriamycin followed by CMF (cyclophosphamide, methotrexate, fluorouracil) and the relative therapeutic contribution of the two drug regimens given at full conventional doses in metastatic breast cancer. PATIENTS AND METHODS:
Mitomycin-C, adriamycin, 5-fluorouracil and leucovorin (L-FAM2) in the treatment of advanced gastric cancer: a phase II study.
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Thirty previously untreated patients with advanced measurable gastric cancer were given a combination chemotherapy consisting of 5-fluorouracil, 400 mg/m2, and leucovorin, 200 mg/m2 iv on days 1 to 3, mitomycin-C, 10 mg/m2 on day 1 (every other cycle) and adriamycin, 40 mg/m2 on day 2, repeated
Detection of adriamycin cardiotoxicity with indium-111 labeled antimyosin monoclonal antibody imaging.
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Myocardial imaging with indium-111 labeled antimyosin monoclonal antibody (antimyosin imaging) has been reported to be useful in the noninvasive detection of myocardial cell necrosis in dilated cardiomyopathy as well as in myocardial infarction and myocarditis. We used antimyosin imaging to detect
[Feasibility of stem cells transplantation through aorta in adriamycin-induced heart failure].
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Stem cells transplantation is a promising strategy for treating myocardial infarction and/or chronic heart failure; however, with respect to nonischemic heart failure, there are some limitations inherent in the current methods of transplantation. In this study, we investigated the feasibility of a
Alteration of matrix metalloproteinases in selective left ventricular adriamycin-induced cardiomyopathy in the pig.
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BACKGROUND
Anthracyclines are widely used in oncogenic therapy. Owing to their cardiotoxic side effects, their application is subdued to dose limitations. Many cardioprotective approaches have failed. This study examined the role of matrix metalloproteinases (MMP) in the remodeling process of
Advanced ovarian cancer with splenic infarct. A case report on diagnostic difficulties and favorable cytotoxic effects.
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Findings obtained with and significance of eight methods of diagnosing splenic infarct combined with advanced ovarian cancer are presented. The internal structures of the affected spleen were visualized only by ultrasonography and computer-assisted roentgen-ray tomography, revealing the enlarged
Effect of carvedilol on pulse pressure and left ventricular hypertrophy in spontaneously hypertensive rats with adriamycin nephropathy.
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Recent studies indicated pulse pressure as a risk factor for left ventricular hypertrophy, myocardial infarction, congestive heart failure and stroke as well as chronic renal failure progression. The present study examined the effects of carvedilol and its combination with captopril on blood
Pharmacology and toxicity of intracarotid adriamycin administration following osmotic blood-brain barrier modification.
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The effect of reversible blood-brain barrier modification on the delivery of Adriamycin to the brain was studied in a rodent and canine model. Pharmacokinetic and physiological studies were done in these animals after a wide range of doses of Adriamycin (0.1 to 1.0 mg/kg) were administered into the
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