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alkaline phosphatase/sarkom
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Decreased alkaline phosphatase in cells transformed by rous sarcoma virus.
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Chick embryo cells transformed by either of two strains of Rous sarcoma virus (Bryan high titer or Schmidt-Ruppin) have low levels of alkaline phosphatase activity compared with nontransformed chick embryo cells. Essentially no differences in acid phosphatase activity were observed between these
Prognostic significance of alkaline phosphatase measurements in patients with osteogenic sarcoma receiving chemotherapy.
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During the period January 1975 to August 1977, alkaline phosphatase levels in 30 patients with osteogenic sarcoma were closely followed in an attempt to determine if these measurements had clinical value in predicting the course of patients with this disease. Of 17 patients with elevated
1,25-Dihydroxyvitamin D3 increases bone alkaline phosphatase isoenzyme levels in human osteogenic sarcoma cells.
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The specific activity of alkaline phosphatase was increased in two human osteogenic sarcoma cell lines, SAOS and TE85, after treatment with 1,25 dihydroxy-vitamin D3 (1,25(OH)2D3). Enzyme activity increased when the cells were incubated with concentrations of 1,25(OH)2D3 between 10(-9) and 10(-7) M
Human osteogenic sarcoma: fine structural localization of alkaline phosphatase.
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The localization of alkaline phosphatase in eight osteogenic sarcomas of osteoblastic. chondroblastic, and fibroblastic type was investigated at the fine structural level using beta-glycerophosphate as substrate and lead as capturing ion. Final product marking localization of alkaline phosphatase
Correlation between MRI appearances and serum alkaline phosphatase levels in Osteogenic sarcoma.
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BACKGROUND
Magnetic resonance imaging is a pictorial depiction of the patho-anatomy of a bony lesion. As different parts of the tumor in Osteogenic sarcoma concurrently undergo various biological processes i.e. osteoblastic new bone formation, cell death, necrosis, bony destruction and
Localization of alkaline phosphatase in subcellular structures of human osteogenic sarcomas.
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Electron microscopic study of osteogenic sarcomas has revealed association of the product of the reaction for alkaline phosphatase with membranous structures. The structural and function polymorphism of osteogenic sarcoma cells is also shown.
SERUM VALUES OF ALKALINE PHOSPHATASE AND LACTATE DEHYDROGENASE IN EWING'S SARCOMA.
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OBJECTIVE
To study the relationship between the serum levels of alkaline phosphatase (AP) and lactate dehydrogenase (LDH), and the percentage of tumor necrosis (TN) in patients with Ewing´s Sarcoma (ES) .
METHODS
This is a case series with retrospective evaluation of patients with diagnosis of ES
Synthesis and biological evaluation of tetramisole analogues as inhibitors of alkaline phosphatase of the 6-thiopurine-resistant tumor sarcoma 180/TG.
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Tetramisole and its analogues are potent inhibitors of alkaline phosphatase, including isoenzymes of Sarcoma 180/TG which appear to be involved in the mechanism of resistance of this neoplastic cell line to the 6-thiopurines. To determine the requirement for the thiazole ring system of tetramisole
An ultrastructural study of alkaline phosphatase in a transplantable rat osteogenic sarcoma.
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Alkaline phosphatase (AP) has been demonstrated by combined electron microscopy and histochemistry in a transplantable rat osteogenic sarcoma, using a modified Gomori technique (Salomon, 1974). During the early stages of growth of subcutaneously implanted tumors, AP was detected in intracellular
Intracellular localization and heterogeneity of alkaline phosphatase of Yoshida ascites sarcoma.
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Spontaneous osteogenic sarcoma in Oryctolagus cuniculus with elevated serum alkaline phosphatase.
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Serum alkaline phosphatase in malignant bone tumours (osteosarcoma, chondrosarcoma, fibrosarcoma, Ewing's sarcoma).
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Solubilization and partial purification of alkaline phosphatases of sarcoma 180-TG ascites cells.
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Alkaline phosphatase activities of 6-thiopurine-sensitive and -resistant sublines of Sarcoma 180.
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Alkaline phosphatase in serum and tumour of rats bearing a hormone-responsive transplantable osteogenic sarcoma.
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