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alstonia boonei/antimykotikum
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Therapeutic effects of various solvent fractions of Alstonia boonei (apocynaceae) stem bark on Plasmodium berghei-induced malaria.
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Malaria, the most important parasitic disease afflicting man is the leading cause of mortality and morbidity in the world. Chemotherapy remains the mainstay for the treatment and prevention of the disease in the absence of an effective vaccine. The incidence of resistance of malaria parasites to
Antifungal activity of venenatine, an indole alkaloid isolated from Alstonia venenata.
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The indole alkaloid venenatine exhibited antifungal activity against some plant pathogenic and saprophytic fungi. Venenatine in an aqueous acetic acid solution inhibited spore germination of all the 10 tested fungi, Fusarium udum, Alternaria brassicicola, Ustilago cynodontis and Aspergillus flavus
Dose-dependent therapeutic antiinfectives from ethnomedicines of bay islands.
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BACKGROUND
The methanol extract of Ophirrhiza nicobarica, Alstonia macrophylla and Mallotus peltatus, ethnomedicines of Little Andaman, were investigated for antiinfective, antiinflammatory and antioxidant activities.
METHODS
Toxicity was determined in cells and in an animal model. Antiviral,
Monoterpenoid indole alkaloids from Alstonia rupestris with cytotoxic, anti-inflammatory and antifungal activities.
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Phytochemical investigation of the 70% EtOH extract of the leaves of Alstonia scholaris afforded seven new monoterpenoid indole alkaloids: scholarisins I-VII (1-7), and three known compounds: (3R,5S,7R,15R,16R,19E)-scholarisine F (8), 3-epi-dihydro- corymine (9), and
Monoterpenoid indole alkaloids from Alstonia rupestris with cytotoxic, antibacterial and antifungal activities.
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A chemical investigation of the 80% EtOH extract of the aerial plant of Alstonia rupestris afforded four new monoterpenoid indole alkaloids, 6,7-epoxy-8-oxo-vincadifformine (1), 11-acetyl-6,7-epoxy-8-oxo-vincadifformine (2), 11-hydroxy-14-chloro-15-hydroxy-vincadifformine (3), and perakine
Synthesis, characterization and evaluation of antimicrobial efficacy and brine shrimp lethality assay of Alstonia scholaris stem bark extract mediated ZnONPs.
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Alstonia scholaris is one of the most important medicinal plants and herein, we present the synthesis of zinc oxide nanoparticles using the bark extract of Alstonia scholaris, and evaluation of their antimicrobial efficacy. Stable ZnO nanoparticles were formed by treating 90 mL of 1 mM zinc nitrate
Antiviral Cystine Knot α-Amylase Inhibitors from Alstonia scholaris.
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Cystine knot α-amylase inhibitors are cysteine-rich, proline-rich peptides found in the Amaranthaceae and Apocynaceae plant species. They are characterized by a pseudocyclic backbone with two to four prolines and three disulfides arranged in a knotted motif. Similar to other knottins, cystine knot
Evaluation of herbal antimalarial MAMA decoction-amodiaquine combination in murine malaria model.
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BACKGROUND
Co-administration of amodiaquine with MAMA decoction (MD), an herbal antimalarial drug comprising the leaves of Mangifera indica L. (Anacardiaceae), Alstonia boonei De Wild (Apocynaceae), Morinda lucida Benth (Rubiaceae) and Azadirachta indica A. Juss (Meliaceae) was investigated. The
Potential of a Khaya ivorensis -Alstonia boonei extract combination as antimalarial prophylactic remedy.
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BACKGROUND
The decoction of the combined stem barks of Khaya ivorensis A. Chev. (Meliaceae) and Alstonia boonei De Wild (Apocynaceae) has a history of use in traditional medicine of central Cameroon for malaria treatment but also for the prevention of the disease.
OBJECTIVE
The purpose of this
Anti-Proliferative Activity of Triterpenoids and Sterols Isolated from Alstonia scholaris against Non-Small-Cell Lung Carcinoma Cells.
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(1) Background: In China and South Asia, Alstonia scholaris (Apocynaceae) is an important medicinal plant that has been historically used in traditional ethnopharmacy to treat infectious diseases. Although various pharmacological activities have been reported, the anti-lung cancer components of A.
Management of corm-rot disease of Gladiolus by plant extracts.
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A pot experiment was conducted to evaluate the efficacy of aqueous extracts of six plant species, namely Azadirachta indica A. Juss. (neem), Alstonia scholaris (L.) R. Br., Lawsonia alba Lam., Allium cepa L., A. sativum L. and Zingiber officinale Roscoe, and a systemic fungicide carbendazim 50%
Ethanolic extracts of Tinospora cordifolia and Alstonia scholaris show antimicrobial activity towards clinical isolates of methicillin-resistant and carbapenemase-producing bacteria.
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The aim of this study was to determine the in vitro antimicrobial activity of crude extracts of three plants from Ayurveda tradition (Tinospora cordifolia, Alstonia scholaris, Crataeva nurvala) against reference microbial strains and clinical isolates of methicillin-resistant Staphylococcus aureus
Phytochemical and antimicrobial study of Alstonia scholaris leaf extracts against multidrug resistant bacterial and fungal strains.
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In the present study, Alstonia scholaris leaves were explored for phytochemical constituents, antibacterial and antifungal potentials. Phytochemical screening of the extracts established the presence of glycosides, alkaloids, saponins, terpenoids, anthraquinones, reducing sugars and steroids which
Phytochemical screening of Alstonia venenata leaf and bark extracts and their antimicrobial activities
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Alstonia venenata is a plant commonly found in South India and used in traditional medicine. The aim of this study was to characterize the phytochemicals present in A. venenata leaf and bark extracts and study their antimicrobial activities. Solvent extractions with Soxhlet apparatus of leaves and
Phytochemical screening of Alstonia scholaris leaf and bark extracts and their antimicrobial activities
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Alstonia sholaris is an evergreen tree commonly found in South East Asia. In traditional medicine pharmacological activities are attributed to the leaves and bark of this plant. The aim of this study is characterizing the chemicals present in A. sholaris leaves and bark extracts and study their
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