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15 resultater
Ester and amide substituted (2,3-dihydro-4-(3-oxo-1-cyclohexen-1-yl)phenoxy)alkanoic acids and their salts
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BACKGROUND OF THE INVENTION
Trauma to the brain or spinal cord caused by physical forces acting on the skull or spinal column, by ischemic stroke, arrested breathing, cardiac arrest, Reye's syndrome, cerebral thrombosis, cerebral embolism, cerebral hemorrhage, encephalomyelitis, hydrocephalus,
Amides of [(5,6-dichloro-3-oxo-9-alpha-substituted-2,3,9,9-alpha-tetrahydrofluoren -7-yl-oxyl]acetic acids, and pharmaceutical compositions thereof
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BACKGROUND OF THE INVENTION
Trauma to the brain or spinal cord caused by physical forces acting on the skull or spinal column, by ischemic stroke, arrested breathing, cardiac arrest, Reye's syndrome, cerebral thrombosis, cerebral embolism, the neurological problems caused by AIDS, cerebral
Synthetic peptide amides
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FIELD OF THE INVENTION
The invention relates to synthetic peptide amides incorporating D-amino acids in the peptide chain and more particularly to such synthetic peptide amides that are kappa opioid receptor agonists, and methods for their use as prophylactic and therapeutic agents.
BACKGROUND
Kappa
Synthetic peptide amides
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FIELD OF THE INVENTION
The invention relates to synthetic peptide amides incorporating D-amino acids in the peptide chain and more particularly to such synthetic peptide amides that are kappa opioid receptor agonists, and methods for their use as prophylactic and therapeutic agents.
BACKGROUND
Kappa
Synthetic peptide amides
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FIELD OF THE INVENTION
The invention relates to synthetic peptide amides incorporating D-amino acids in the peptide chain and more particularly to such synthetic peptide amides that are kappa opioid receptor agonists, and methods for their use as prophylactic and therapeutic agents.
BACKGROUND
Kappa
Synthetic peptide amides
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FIELD OF THE INVENTION
The invention relates to synthetic peptide amides incorporating D-amino acids in the peptide chain and more particularly to such synthetic peptide amides that are kappa opioid receptor agonists, and methods for their use as prophylactic and therapeutic agents.
BACKGROUND
Kappa
Synthetic peptide amide dimers
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FIELD OF THE INVENTION
The invention relates to synthetic peptide amides incorporating D-amino acids in the peptide chain and more particularly to such synthetic peptide amides that are kappa opioid receptor agonists, and methods for their use as prophylactic and therapeutic agents.
BACKGROUND
Kappa
Synthetic peptide amides for pain
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FIELD OF THE INVENTION
The invention relates to synthetic peptide amides incorporating D-amino acids in the peptide chain and more particularly to such synthetic peptide amides that are kappa opioid receptor agonists, and methods for their use as prophylactic and therapeutic agents.
BACKGROUND
Kappa
4-Hydroxy pyrrolidin-2-onyl-amides
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The present invention concerns a new process for the preparation of pyrrolidine derivatives.
The pyrrolidine derivatives with which the present invention is concerned are compounds of the general formula: ##STR2## wherein n is 1, 2 or 3, R.sub.1 and R.sub.2, which can be the same or different, are
Coumarin-amide derivatives and its preparation, said drug composition and its use
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TECHNICAL FIELD
The present invention relates to novel coumarins, their carboxamide derivatives, the preparation method thereof and the pharmaceutical compositions containing them, and their use as medicaments for kidney protection, as well as for the treatment of hypertension,
Aromatic and heteroaromatic substituted amides
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FIELD OF INVENTION
The invention relates to a compound of formula ##STR1##
wherein R.sup.1 is selected from the group consisting of hydrogen and fluoro. Compounds of formula 1, and pharmaceutically acceptable acid addition salts thereof, have been shown to mediate the Neurokinin 1 (NK-1, substance
2,3-di-substituted-5,6-dihydroimidazo [2,1-b] thiazole, its salts, production thereof and anti-inflammatory agent containing the same
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This invention relates to novel imidazothiazole derivatives, their salts, a method for the production thereof, and anti-inflammatory compositions containing the same. More particularly, this invention relates to 2,3-di-substituted-5,6-dihydroimidazo [2,1-b] thiazole, its salts, a method for the
2,-3-Di-substituted-5,6-dihydroimidazo [2,1-b] thiazole, its salts, production thereof and anti-inflammatory agent containing the same
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This invention relates to novel imidazothiazole derivatives, their salts, a method for the production thereof, and anti-inflammatory compositions containing the same. More particularly, this invention relates to 2,3-di-substituted-5,6-dihydroimidazo [2,1-b] thiazole, its salts, a method for the
Production method for isoquinoline derivatives and salts thereof
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TECHNICAL FIELD
The present invention relates to a method for producing an isoquinoline derivative or a salt thereof which is useful for preventing and treating cerebrovascular disorders such as cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage, and cerebral edema, particularly as a
Production method for isoquinoline derivatives and salts thereof
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This application is a National Stage of PCT/JP11/069,187 filed Aug. 25, 2011 and claims the benefit of JP 2010-189392 filed Aug. 26, 2010.
TECHNICAL FIELD
The present invention relates to a method for producing an isoquinoline derivative or a salt thereof which is useful for preventing and treating
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