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8 resultater
Non-heterocyclic .beta.-phenyl-.alpha.-aminopropionic acid n-phenyl amides for treatment of neurotoxic injury
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FIELD OF THE INVENTION
This invention is in the field of clinical neurology and relates specifically to compounds, compositions and methods for neuroprotective purposes such as controlling brain damage which occurs during periods of anoxia or ischemia associated with stroke, cardiac arrest or
Compounds and compositions for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer
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FIELD
Disclosed herein is {[5-(3-fluorophenyl)-3-hydroxypyridine-2-carbonyl]-amino}acetic acid and the ester and amide prodrugs thereof, that can stabilize hypoxia inducible factor-2 alpha (HIF-2.alpha.) and thereby provide a method for treating cancer. Further disclosed are compositions which
4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide
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FIELD OF THE INVENTION
The present invention relates to 4-hydroxy-4-methyl-piperidine-1-carboxylic acid(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide, which is a compound of formula
##STR00002## and to pharmaceutically acceptable acid addition salts thereof. This compound is generically
New 1-(alkoxybenzyl)piperazine amide compounds
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The invention relates to new 1-(alkoxybenzyl)piperazine amide compounds, to process for preparing these and to pharmaceutical compositions containing them.
Many 1-(alkoxybenzyl)piperazine amide compounds are known in the literature.
Thus, some compounds of general formula (a): ##STR2## are described
Amide derivatives of substituted quinoxaline 2,3-diones as glutamate receptor antagonists
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BACKGROUND OF THE INVENTION
The present invention concerns novel amide derivatives of substituted quinoxaline 2,3-diones having utility as glutamate receptor antagonists. The fused ring quinoxaline 2,3-dione system is substituted at the a- or b-position by amide derivatives. The compounds are active
Amide derivatives of substituted quinoxaline 2, 3-diones as glutamate receptor antagonists
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BACKGROUND OF THE INVENTION
The present invention concerns novel amide derivatives of substituted quinoxaline 2,3-diones having utility as glutamate receptor antagonists. The fused ring quinoxaline 2,3-dione system is substituted at the a- or b-position by amide derivatives. The compounds are active
Method of combatting osteoporosis in mammalian subjects, utilizing organic boron compounds
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to a method for preventing and/or treating osteoporosis and other disease states in animal subjects, utilizing organic boron compounds.
2. Description of the Related Art
The adult skeleton is composed of 80% cortical
Treating cognition with, aminocyclopropanecarboxylic derivatives
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to the field of neuropsychiatry and relates specifically to methods for memory enhancement and treatment of memory deficits consequent to neurological disorders.
2. Description of the Background Art
The N-methyl-D-aspartate
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