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Side 1 fra 394 resultater
Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides
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INTRODUCTION
This invention relates generally to the field of chemotherapeutic agents and more particularly to pentapeptide heterocyclic and halophenyl amide derivatives of dolastatin 10.
BACKGROUND OF THE INVENTION
Ancient marine invertebrate species of the Phyla Bryozoa, Molluska, and Porifera
Antimitotic amides for the treatment of cancer and proliferative disorders
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TECHNICAL FIELD OF THE INVENTION
The present invention relates to biologically active chemical compounds, namely heteroaryl amides for treating proliferative disorders such as cancer.
BACKGROUND
Cancer is currently the second leading cause of death in the United States of America, the European Union
Treatment of skin diseases and tumors with esters and amides of monocarboxylic acids
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BACKGROUND OF THE INVENTION
Certain classes of noninfections inflammatory and hyperpigmentation diseases of the skin, thermal injuries of the skin, and premalignant skin tumors induced by ultraviolet or x-ray radiation or viruses, particularly those diseases which are multifactorial with a genetic
Pharmaceutical composition comprising amide derivative inhibiting the growth of cancer cells and non-metallic salt lubricant
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FIELD OF THE INVENTION
The present invention relates to a pharmaceutical composition comprising an amide derivative or its pharmaceutically acceptable salt inhibiting the growth of cancer cells and a non-metallic salt lubricant.
BACKGROUND OF THE INVENTION
The epidermal growth factor receptor (EGFR)
Pharmaceutical composition comprising amide derivative inhibiting the growth of cancer cells and non-metallic salt lubricant
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a National Stage of International Application No. PCT/KR2012/003970 filed May 18, 2012, claiming priority based on Korean Patent Application No. 10-2011-0054685, filed Jun. 7, 2011, the contents of which are incorporated herein by reference
Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression
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The invention relates to the use of pyridyl aklane, pyridyl alkene and/or pyridyl alkine acid amides, especially in the treatment of tumor conditions and/or as cytostatic agents or as immunosuppressive agents as well as medicaments with an amount of these compounds in combination with other
Bis(thio-hydrazide amide) salts for treatment of cancers
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BACKGROUND OF THE INVENTION
Many drugs are now available to be used in the treatment of cancer. However, in many cases the cancer fails to respond to the anti-cancer therapy or its growth and/or metastasis is only slowed. Even when a tumor initially responds to an anti-cancer therapy by decreasing
Tumor inhibiting tetrapeptide bearing modified phenethyl amides
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INTRODUCTION
This invention relates generally to the field of antineoplastic compounds, and more particularly to the design and synthesis of selected tetrapeptides bearing modified phenethylamides, exhibiting tumor inhibitory effects.
BACKGROUND OF THE INVENTION
Ancient marine invertebrate species
Combination with bis(thiohydrazide amides) for treating cancer
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BACKGROUND OF THE INVENTION
Cancer is a group of diseases that are characterized by uncontrolled cell division. This uncontrolled division can compromise the function of an organism and ultimately may cause its death.
On average, in the United States, men have a 1 in 2 lifetime risk of developing
Bis(thio-hydrazide amide) salts for treatment of cancers
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BACKGROUND OF THE INVENTION
Many drugs are now available to be used in the treatment of cancer. However, in many cases the cancer fails to respond to the anti-cancer therapy or its growth and/or metastasis is only slowed. Even when a tumor initially responds to an anti-cancer therapy by decreasing
BIS (thio-hydrazide amide) salts for treatment of cancers
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BACKGROUND OF THE INVENTION
Many drugs are now available to be used in the treatment of cancer. However, in many cases the cancer fails to respond to the anti-cancer therapy or its growth and/or metastasis is only slowed. Even when a tumor initially responds to an anti-cancer therapy by decreasing
Bis(thio-hydrazide amide) salts for treatment of cancers
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BACKGROUND OF THE INVENTION
Many drugs are now available to be used in the treatment of cancer. However, in many cases the cancer fails to respond to the anti-cancer therapy or its growth and/or metastasis is only slowed. Even when a tumor initially responds to an anti-cancer therapy by decreasing
Thiazolidinone amides, thiazolidine carboxylic acid amides, and serine amides, including polyamine conjugates thereof, as selective anti-cancer agents
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FIELD OF THE INVENTION
The present invention relates to novel thiazolidinone amides, novel thiazolidine carboxylic acid amides, methods of making these compounds, and uses thereof, particularly for treating various cancers including but not limited to prostate, breast, ovarian, and skin
Human cancer inhibitory peptide amides
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INTRODUCTION
This invention relates generally to the field of cancer chemotherapy and more particularly to the synthesis of unique pentapeptide amides and tetrapeptide amide derivatives of dolastatin 10 which may be useful in chemotherapy.
BACKGROUND OF THE INVENTION
Ancient marine invertebrate
Human cancer inhibitory peptide amides
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INTRODUCTION
This invention relates generally to the field of cancer chemotherapy and more particularly to the synthesis of unique pentapeptide amides and tetrapeptide amide derivatives of dolastatin 10 which may be useful in chemotherapy.
BACKGROUND OF THE INVENTION
Ancient marine invertebrate
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