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Mesenchymal Stem Cell Infusion for COVID-19 Infection

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All patients will receive 2x10^6 cells/kg on days 1 and day 7 (if needed). The study will be divided in 2 phases. In the first phase, 10 patients will be included and randomized to 2 groups (5 Treatment arm; 5 Control Arm) and receive 2 x10^6 cells/kg MSCs on days 1 and 7 in addition to standard

Exchange Transfusion Versus Plasma From Convalescent Patients With Methylene Blue in Patients With COVID-19

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Study Tools AND/ OR procedure The patients were subjected to the following: Clinical parameters: Complete history taking and thorough clinical examination 1. Laboratory parameters: 2. CBC with differential counts. 3. Reticulocytic count. 4. Blood film for shistocytes. 5. Serum ferritin and

Protective Effect of Aspirin on COVID-19 Patients

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1. COVID-19 has a high infection rate and mortality, and serious complications such as heart injury cannot be ignored. At present, the scale and harm of COVID 19 (Novel coronavirus pneumonia (NCP) has far surpassed that of SARS in 2003, with more than 80,000 cases confirmed in China and 3,119 deaths

Efficacy of Nafamostat in Covid-19 Patients (RACONA Study)

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Purpose: SARS-Cov-2 enters the lung cells by binding to ACE-2 and activating the protease TMPRSS2, which, therefore, can be a target for antiviral treatment. Accordingly, TMPRSS2 inhibitors prevent SARS-CoV cell entry in vitro. The most potent such inhibitors, nafamostat is being used as

Mechanical Thrombectomy in Acute Ischemic Stroke Beyond the Time of Window

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Background Expanding time window using the emerging technologies for mechanical thrombectomy can improve chances of achieving successful thrombectomy and improve clinical outcome in patients that would have only received conservative treatment. The aim of this work is to evaluate the effectiveness

Polidocanol Foam Versus Rubber Band Ligation in the Treatment of Hemorrhoidal Disease

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INTRODUCTION Hemorrhoids are normal vascular structures in the anal canal, arising from a cushion of dilated arteriovenous channels and connective tissues, that drains into the superior and inferior hemorrhoidal veins. Their main function is to maintain anal continence, serve as a protection for the

AntiCoagulants and COGnition

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Detailed Description: Vitamin K antagonists (VKAs) are commonly used for their role in hemostasis by interfering with vitamin K cycle decreasing the bioavailability of the vitamin K active form. In addition to a role in blood coagulation, vitamin K participates in brain health and function by

Co-ultra PEALut Enhances Neuronal Recovery Following Moderate Traumatic Brain Injury

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Study Setting All patients affected by moderate TBI (Glasgow Coma Score 9-13) admitted to the neurosurgical department of the University Hospital of Messina, Italy, will be screened for recruitment. Ethics The institutional review board (IRB) approved the study. Written consent will be obtained from
- Objective: To determine the effect of the daily addition of five mL of an O3 highly concentrated substance (EicosaPentaenoic Acid - EPA: 2.25 g and DocosaHexaenoic Acid - DHA: 1.08 g), to the standard enteral nutrition diet during RT (5-7 weeks), on the Quality of Life (QoL) and Functionality (Fx)

Study of Neurodegenerative Diseases Induced Stem Cells in Patients and Healthy Family Controls.

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1. INTRODUCTION Neurological and neurodegenerative diseases have a major impact in families and in the national health service due to the lack in many cases of effective and long-lasting therapies. The lack of these therapeutic strategies is due in large part to the difficulty of modeling these

Near Infra-red Spectroscopy for Detection of Intracranial Haematoma

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Introduction: Fall with head injury is becoming an epidemic challenge especially with the ageing population. Contributing factors for mortality and poor functional outcome included development of cerebral contusion and delayed traumatic intracerebral haematoma. There is a higher prevalence

Tranexamic Acid to Prevent OpeRation in Chronic Subdural Hematoma

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1. INTRODUCTION AND RATIONALE Chronic subdural hematoma (cSDH) is a frequently occurring neurological disease of the elderly and common in daily neurosurgical practice. It consists of an extracerebral encapsulated collection of mostly liquefied old hematoma, located between the dura and arachnoid.

Early Rehabilitation Program In Critically Ill Chronic Obstructed Airway Disease Patients

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Mechanical ventilation (MV) in intensive care units (ICUs) essential in the management of respiratory failure, can result in respiratory dysfunction and inspiratory muscle weakness. Like any other striated muscle, respiratory muscle mass is affected by contractile inactivity. In fact, the

Use of PRP in Endometrial Reconstruction

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The objective is to know the effect of these regenerative factors obtained from Platelet-Rich Plasma in an immunodeficient murine model with AS/EA Blood from patients with Asherman's Syndrome (AS) and Endometrial Atrophy (EA) will be collected, maintained under anticoagulant solution and after

Long-term Effect of Motor Cortex Stimulation in Patients Suffering From Chronic Neuropathic Pain

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2.1 Study protocol In 2003, an observational study protocol was set up in the university medical centers of Nijmegen and Groningen, the Netherlands, in order to study the effects of MCS in patients that suffered from chronic neuropathic pain. Patients were included between 2005 and 2013 when they
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