anticonvulsants/natskygge

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Anticonvulsant activity of solasodine isolated from Solanum sisymbriifolium fruits in rodents.

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BACKGROUND Solanum sisymbriifolium Lam. (Solanaceae), commonly known as sticky nightshade, is traditionally used for central nervous system (CNS) disorders. Although solasodine has been isolated from this plant, little is known about its anticonvulsant and CNS depressant actions. OBJECTIVE We

Zebrafish bioassay-guided microfractionation identifies anticonvulsant steroid glycosides from the Philippine medicinal plant Solanum torvum.

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Medicinal plants used for the treatment of epilepsy are potentially a valuable source of novel antiepileptic small molecules. To identify anticonvulsant secondary metabolites, we performed an in vivo, zebrafish-based screen of medicinal plants used in Southeast Asia for the treatment of seizures.

Potato (Solanum tuberosum) juice exerts an anticonvulsant effect in mice through binding to GABA receptors.

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Naturally occurring benzodiazepines have been identified in regular food such as wheat and potato, but there is still no evidence that potato extracts can affect CNS responses in vivo. Here we found that undiluted potato juice and potato juice diluted with saline 1 : 2 administered 10 min

Effect of alkaloids of Solanum melongena on the central nervous system.

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Crude alkaloidal fraction isolated from the leaves of Solanum melongena was screened for its effects on the central nervous system. It exhibited significant analgesic effect and some CNS depression but no anticonvulsant action. The analgesic effects were of non-narcotic type. LD50 was estimated to

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