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antispasmodic/betændelse
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Antispasmodic 1,2-Diols and 1,2,3-triols
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to the field of pharmaceutical compositions and their use to relieve the spasms associated with pain. It describes pharmaceutical compositions comprising an antispasmodic agent alone or in combination with analgesic
N'-substituted derivatives of 4'-(N-piperazinylmethyl) spiro dibenzocycloheptadi- (or tri-) ene-5, 2'-dioxolane (1',3') their method of preparation and their application in therapeutics
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The present invention relates to new N'-substituted derivatives of 4'-(N-piperazinylmethyl)spiro dibenzocycloheptadi- (or tri-) ene-5,2'-dioxolane (1',3').
The compounds have the formula: ##STR4## in which: Z represents a --CH.sub.2 --CH.sub.2 -- group or a --CH.dbd.CH-- group, and
R
N-substituted derivatives of 4 (N-piperazinylmethyl) spiro dibenzocycloheptadi- (or tri-) ene-5, 2-dioxolane (1,3) their method of preparation and their application in therapeutics
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The present invention relates to new N'-substituted derivatives of 4'-(N-piperazinylmethyl)spiro dibenzocycloheptadi- (or tri-) ene-5,2'- dioxolane (1',3').
The compounds have the formula: ##STR4## in which: Z represents a --CH.sub.2 --CH.sub.3 -- group or a --CH.dbd.CH-- group, and
R
N'-substituted derivatives of 4'-(N-piperazinylmethyl)spiro dibenzocycloheptadi- (or tri-) ene-5,2'-dioxolane(1',3')
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The present invention relates to new N'-substituted derivatives of 4'-(N-piperazinylmethyl)spiro dibenzocycloheptadi- (or tri-) ene-5,2'-dioxolane (1',3').
The compounds have the formula: ##STR4## in which: Z represents a --CH.sub.2 --CH.sub.2 --group or a --CH=CH--group, and
R represents:
Methyl,
Diphenyl compounds which inhibit arachidonic acid metabolism, and their use in pharmaceutical compositions
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The invention relates to pharmaceutical compositions containing liopxygenase- and prostaglandin H synthase-inhibiting active ingredients for preferably topical application in human and veterinary medicine. They are used in particular for the treatment of inflammatory skin diseases of non-microbial
Synthetic endogenous cannabinoids analogues and uses thereof
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STATEMENT OF THE INVENTION
The present invention relates to compounds of the general formula (I), to a process for their preparation, to pharmaceutical compositions containing at least one compound of the invention and to the different uses of said compounds.
BACKGROUND OF THE INVENTION
Anandamide
Compounds derived from lidocaine, pharmaceutical compositions, use and method of treatment, prevention or inhibition of disease
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CROSS REFERENCE TO RELATED APPLICATIONS
This is the U.S. National Stage of International Application No. PCT/BR2005/000101, filed Jun. 7, 2005, which was published in English under PCT Article 21(2), and claims benefit of priority of Brazilian Patent Application No. 0404222-0, filed Jun. 7, 2004,
Therapeutic and nutritional compositions for functional gastrointestinal disorders
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This application is a U.S. national stage of PCT/EP2015/070579 filed on 9 Sep. 2015, which claims priority to and the benefit of European Patent Application No. 14185003.2 filed on 16 Sep. 2014, the contents of which are incorporated herein by reference in their entireties.
STATE OF THE
1-(2-hydroxyaryl)-alkane-1-on-oximes-procedure of preparation and use in pharmaceuticals
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BACKGROUND OF THE INVENTION AND PRIOR ART STATEMENT
This invention relates partially to new 1-(2-hydroxyaryl)-alkane-1-on-oximes, processes for their preparation, and their applicability to pharmaceutical preparations. The compounds in their own right and, consequently, the pharmaceutical products
Substituted alkyltetraamine derivatives
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FIELD OF THE INVENTION
The present invention relates to substituted alkyltetraamine derivatives which are useful as a tachykinin antagonist.
BACKGROUND OF THE INVENTION
Tachykinin is a general term for a group of peptides having similar structures. Substance P (SP), neurokinin A (NKA) and neurokinin
Implantable or insertable medical devices for controlled drug delivery
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TECHNICAL FIELD
This invention generally relates to medical devices, and more particularly to implantable or insertable medical devices and methods for their manufacture.
BACKGROUND INFORMATION
Numerous medical devices have been developed for the delivery of therapeutic agents to the body. In
Implantable or insertable medical devices for controlled drug delivery
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TECHNICAL FIELD
This invention generally relates to medical devices, and more particularly to implantable or insertable medical devices and methods for their manufacture.
BACKGROUND INFORMATION
Numerous medical devices have been developed for the delivery of therapeutic agents to the body. In
1-(2'-Aroyl eth-1'yl) 2-(4"-acetamido piperazine-1"yl methyl) benzimidazoles and their therapeutical applications
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The present invention concerns 1-(2'-aroyl eth-1' yl) 2-(4"-acetamido piperazine-1" yl methyl) benzimidazoles, their method of preparation and their application in therapeutics.
The compounds of the invention correspond to the following general formula (I): ##STR2## in which: Ar designates:
A phenyl
New 1-(2'-aroyl eth-1' yl) 2-(4"-acetamido piperazine-1" yl methyl) benzimidazoles, their therapeutical applications and method for their preparation
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The present invention concerns 1-(2'-aroyl eth-1' yl) 2-(4"-acetamido piperazine-1" yl methyl) benzimidazoles, their method of preparation and their application in therapeutics.
THE COMPOUNDS OF THE INVENTION CORRESPOND TO THE FOLLOWING GENERAL FORMULA (I): ##STR2## in which Ar designates
A phenyl
Therapeutic application of N-substituted 2-aminomethylene-1,3-indanediones
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to N-substituted 2-aminomethylene-1,3-indanediones and their therapeutic application.
2. Discussion of the Background
The present invention relates to products having the structural formula ##STR2## in which R.sub.1
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