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Inorganic Arsenic Exposure Decreases Muscle Mass and Enhances Denervation-Induced Muscle Atrophy in Mice
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Arsenic is a toxic metalloid. Infants with a low birth-weight have been observed in areas with high-level arsenic in drinking water ranging from 463 to 1025 μg/L. A distal muscular atrophy side effect has been observed in acute promyelocytic leukemia patients treated with arsenic trioxide
Exposure of low-concentration arsenic induces myotube atrophy by inhibiting an Akt signaling pathway.
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Arsenic, a widely distributed toxic metalloid, has been found to be associated with the low-birth-weight infants and the impairment of muscle regenerative capacity in areas with high levels of arsenic in drinking water. The distal muscular atrophy is one of side effects of arsenic trioxide
Protective role of Moringa oleifera (Sajina) seed on arsenic-induced hepatocellular degeneration in female albino rats.
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In an attempt to develop new herbal therapy, an aqueous extract of the seed of Moringa oleifera was used to screen the effect on arsenic-induced hepatic toxicity in female rat of Wistar strain. Subchronic exposure to sodium arsenite (0.4 ppm/100 g body weight/day via drinking water for a period of
High fat diet deteriorates the memory impairment induced by arsenic in mice: a sub chronic in vivo study.
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Both arsenic (As) and obesity are associated with brain disorders. However, long term studies to evaluate their concomitant adverse effects on the brain functions are lacking. Present study was conducted to evaluate the long term co-exposure of As and high fat diet (HFD) on memory and brain
[7TH CASE OF CHRONIC ARSENIC POISONING IN BEAJOLAIS VINE-GROWERS COMPLICATED BY CUTANEOUS DEGENERATION WITH MULTIPLE FOCI: BOWEN-TYPE DYSKERATOSIS AND SPINOUS CELL EPITHELIOMA].
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OPTIC ATROPHY AFTER INJECTIONS OF ARSENIC.
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[Polyneyritis: dermopathy and hepatic atrophy due to chronic criminal arsenic poisoning].
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Dimercapto-1-propanesulfonic acid (DMPS) induces metaphase II mouse oocyte deterioration.
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In light of the recent lead contamination of the water in Flint, Michigan and its potential adverse outcomes, much research and media attention has turned towards the safety profile of commonly used chelators. Dimercapto-1-propanesulfonic acid (DMPS) typically used in the treatment of lead, mercury
A Fatal Case of Acute Arsenic Poisoning.
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This manuscript reported a case of fatal arsenic poisoning. A woman with schizophrenia took arsenic-containing "pills," which consisted of arsenic trioxide and realgar (arsenic (II) sulfide) and wrapped with gauze. The victim consumed 1.09 and 0.819 g arsenic on two occasions,
Sensitivity of wild cotton rats (Sigmodon hispidus) to the immunotoxic effects of low-level arsenic exposure.
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Arsenic is a ubiquitous contaminant of many toxic waste sites around the country and experimental animal trials have indicated that arsenic may be immunotoxic to laboratory rodents. Because wild rodents such as the herbivorous cotton rat (Sigmodon hispidus) reside on many of these toxic waste sites,
Organic arsenic-induced Guillain-Barré-like syndrome due to melarsoprol: a clinical, electrophysiological, and pathological study.
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A young woman suffering from sleeping sickness was treated with melarsoprol. Thirty-eight days after the first administration of this organo-arsenic compound, myalgias, distal paresthesias and rapidly progressive weakness developed in all four limbs. Electrophysiological studies were misleading for
Arsenic induces dose-dependent structural and ultrastructural pathological remodeling in the heart of Wistar rats
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Aim Arsenic, an environmental contaminant, represents a public health problem worldwide. Studies have shown its association with molecular mechanisms related to cardiomyocytes redox balance. However, the microstructure and ultrastructure of cardiac tissue, as well as the activity of its antioxidant
[Effect of arsenic toxicity on morphology and viability of enzyme in primary culture of rat hippocampal neurons].
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In order to study the toxic consequences of arsenic at different levels on hippocampal neurons of rat, different doses of sodium arsenite (0, 0.08, 0.40, 2.00 and 10.00 mg/L) were given to observe the changes of viability, morphological and biochemical parameters. The results showed that the
Electrophysiological profile in arsenic neuropathy.
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Comprehensive electrophysiological studies were performed on 13 patients with arsenic neuropathy. The most prominent finding was a marked abnormality in sensory nerve conduction in the presence of moderate abnormalities in motor nerve conduction. The motor nerve conduction studies and needle EMG
Acute and chronic arsenic poisoning associated with treatment of acute promyelocytic leukaemia.
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Seven relapsed and/or refractory acute promyelocytic leukaemia patients were treated by arsenic trioxide (As2O3). Four patients (4/7, 57%) achieved complete remission after one to three cycles of treatment and the most common acute side-effect was fluid retention (in six patients, 86%), including
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