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A phase I study to study arsenic trioxide with radiation and hyperthermia in advanced head and neck cancer.
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OBJECTIVE
Arsenic trioxide [ATO] is a pluripotent drug with potentials to have pro-oxidant, angiogenesis inhibitor, flow inhibitor and radiation sensitizer properties.
METHODS
The present study is a Phase I trial to assess the safety of ATO in advanced or recurrent head and neck cancer treated with
Radiosensitivity enhancement by arsenic trioxide in conjunction with hyperthermia in the EC-1 esophageal carcinoma cell line.
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OBJECTIVE
To explore the effect on radiosensitivity of arsenic trioxide (As₂0₃) in conjunction with hyperthermia on the esophageal carcinoma EC-1 cell line.
METHODS
Inhibition of EC-1 cell proliferation at different concentrations of As₂0₃ was assessed using the methyl thiazolyl blue colorimetric
Medical Reports of the Effects of Arsenic in the Cure of Agues, Remitting Fevers, and Periodic Head-Achs.
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The systematic treatment of 227 cases of arsenic poisoning (encephalitis, dermatitis, blood dyscrasias, jaundice, fever) with 2,3-demercaptopropanol (BAL).
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[Research on experimental therapy of syphilitic infection. The influence of arsenic, mercury, iodine and of fever attacks on the penicillin levels of the blood and urine].
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Observations on the Use of Arsenic in the Intermittent Fevers of a Tropical Climate; to Which Is Prefixed an Account of the Weather, at Sierra Leone, during the Season in Which Such Fevers Are Most Prevalent.
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[Effect of artificial fever on the distribution of arsenic in tissue; preliminary report].
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Intravenous Arsenic for Anginous Forms of Glandular Fever.
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Synergistic teratogenic effects of arsenic and hyperthermia in hamsters.
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Observations on the Use of Arsenic in Intermittent Fevers.
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Cases Illustrating the Efficacy of Arsenic in Intermittent Fever.
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Evaluation on Efficacy and Safety of Arsenic Trioxide Plus Transcatheter Arterial Chemoembolization Versus Transcatheter Arterial Chemoembolization alone for Unresectable Primary Liver Cancer
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Currently, some clinical trials of arsenic trioxide (As203) plus transcatheter arterial chemoembolization (TACE) in the treatment of unresectable primary liver cancer (PLC) had been conducted, but the results were controversial. Therefore, we performed a meta-analysis on 14 clinical trials (1076
[Successful treatment after acute promyelocytic leukemia (APL) syndrome of relapsed API with arsenic trioxide].
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A 52-year-old female was diagnosed with relapsed APL in 2000. After obtaining informed consent, we administered 10 mg/day of arsenic trioxide intravenously. The complications were vomiting, increased transaminase and ATRA syndrome which included high fever, retention of body fluid, pleural effusion,
Toxic epidermal necrolysis after extensive dermal use of realgar-containing (arsenic sulfide) herbal ointment.
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BACKGROUND
Realgar (arsenic sulfide) is thought to be safe with few reports on toxicities or adverse effects and has been used in Traditional Chinese Medicine for many centuries. Serious realgar poisoning is rare, and we report a fatal case resulted from short-term use of realgar-containing herbal
[Oral administration of arsenic trioxide induced molecular remission in relapsed acute promyelocytic leukemia].
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I report on a 21-year-old man with acute promyelocytic leukemia (APL) which relapsed after a therapeutic regimen consisting of tretinoin, daunorubicin, enocitabine, mitoxantrone, and cytarabine. The patient also had severe mental retardation caused by a congenital central nervous system
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