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beta carboline/kræft
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9 resultater
Bis-.beta.-carboline compound and preparation method, pharmaceutical composition and use thereof
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FIELD OF THE INVENTION
The present invention relates to a class of bis-.beta.-carboline alkaloid compounds and pharmaceutically acceptable salts, their preparation, as well as pharmaceutical compositions comprising such compounds, and its application in the preparation of anti-tumor drugs; belongs
Beta-carbolines useful for treating inflammatory disease
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FIELD OF THE INVENTION
This invention relates to beta-carboline compounds, pharmaceutical compositions thereof, and methods of using the compositions for treating disease. The compounds are particularly useful for treating inflammatory disease and cancer.
BACKGROUND OF THE INVENTION
The
Beta carboline derivatives useful in the treatment of proliferative disorders
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FIELD OF THE INVENTION
The invention is in the medical field, more precisely in the field of new therapeutic compounds, more particularly compounds useful in the treatment of proliferative disorders including cancer. The invention relates to alkaloid compounds, more specifically to beta-carboline
Beta-carbolines useful for treating inflammatory disease
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FIELD OF THE INVENTION
This invention relates to beta-carboline compounds, pharmaceutical compositions thereof, and methods of using the compositions for treating disease. The compounds are particularly useful for treating inflammatory disease and cancer.
BACKGROUND OF THE INVENTION
The
Tetrahydro-beta-carboline derivatives, synthesis and use thereof
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TECHNICAL FIELD
The present disclosure relates to derivatives of tetrahydro-.beta.-carbolines and in particular 2-halophenyl, 2,4-dihalophenyl, 3,4-dihalophenyl, 2,6-dihalophenyl and 2,5-dialkoxyphenyl derivatives of tetrahydro-.beta.-carbolines including 2-chlorophenyl, 2-bromophenyl,
N-substituted cycloalkyl and polycycloalkyl polyhydro-.beta.-carboline-phenylalanine- and phenethylamine derivatives
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BACKGROUND OF THE INVENTION
Agents acting at central cholecystokinin (CCK) receptors may induce satiety (Schick, Yaksh and Go, Regulatory Peptides 14:277-291, 1986). They are also expected to act as analgesics (Hill, Hughes and Pittaway, Neuropharmacology 26:289-300, 1987), and as anticonvulsants
1-naphthyl-or 1-dihydroacenaphthenyl-pyrido[B]indoles and uses thereof in treating cancers
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to the fields of organic chemistry and chemotherapeutic compounds. Specifically, the present invention relates to 1-aryl(heteroaryl)pyrido[b]indoles or indole analogs thereof and their uses in treating cancers.
2.
Neuroprotective and anti-proliferative compounds
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FIELD OF THE INVENTION
This invention features pyrrolo-.beta.-carboline derivatives and derivatives of 3-(1H-indol-3-yl)-1H-pyrrole-2,5-dione which are useful in prevention and treatment of degenerative and inflammatory diseases of the central and peripheral nervous systems, by inhibiting axonal
Harmine derivatives, intermediates used in their preparations, preparation processes and use thereof
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FIELD OF INVENTION
This invention belongs to the field of pharmaceutical compounds, and specifically relates to alkaloid compounds, and more specifically, to harmine derivatives of formula (I), intermediates used in their preparation, processes for preparing the same and uses thereof.
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