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Molecular pathology of brain edema after severe burns in forensic autopsy cases with special regard to the importance of reference gene selection.

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Brain edema is believed to be linked to high mortality incidence after severe burns. The present study investigated the molecular pathology of brain damage and responses involving brain edema in forensic autopsy cases of fire fatality (n = 55) compared with sudden cardiac death (n = 11), mechanical

Randomised control trial of compression interventions for managing hand burn edema, as measured by bioimpedance spectroscopy

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Introduction: Compression, a common treatment of choice for the management of edema, is one intervention which is applied with little objective understanding of the optimal parameters of application or efficacy in acute burn

Terahertz Imaging of Cutaneous Edema: Correlation With Magnetic Resonance Imaging in Burn Wounds.

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In vivo visualization and quantification of edema, or 'tissue swelling' following injury, remains a clinical challenge. Herein, we investigate the ability of reflective terahertz (THz) imaging to track changes in tissue water content (TWC)-the direct indicator of edema-by comparison to

The role of interstitial starling forces in the pathogenesis of burn edema.

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The formation and sustainability of burn edema require substantial change in net microvascular forces. We directly measured interstitial hydrostatic pressure (Pi) and total interstitial absorptive pressure (Pi + IIi), in dermis of anesthetized sheep, before and after a 70% to 85% total body surface

A Descriptive Study of the Temporal Patterns of Volume and Contents Change in Human Acute Burn Edema: Application in Evidence-Based Intervention and Research Design.

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Edema after burn contributes significantly to burn wound depth conversion. In humans after burn injury, there is a lack of detailed understanding of the contents and temporal changes in volume of acute tissue edema. The novel findings of these studies relate to the collection of edema fluid after

Bioimpedance spectroscopy is a valid and reliable measure of edema following hand burn injury (Part 1 - Method validation).

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The assessment of swelling following burn injury is complicated by the presence of wounds and dressings, and due to patients experiencing significant pain and impaired movement. There remains a lack of sensitive objective measures for edema in patients presenting with hand burn injury.

Burn edema is accentuated by a moderate smoke inhalation injury in sheep.

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We determined the lung and systemic response of a moderate smoke inhalation injury combined with a 15% total body surface third-degree burn compared with a burn alone and inhalation alone. Adult sheep were prepared with chronic lung and bilateral prefemoral soft tissue lymph fistula. The burn was

[Relation between changes in monoamine transmitters and brain edema after thermal burns in rats].

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The HPLC with electro-chemical detector was employed to determine the change in monoamine transmitters and their metabolites murine hypothalamus, brainstem and spinal cord after burn. Also the pathological changes after burn in three brain parts was observed with photomicrograph and

The study of burn wound edema using dichromatic absorptiometry.

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Burn wound edema is a source of major morbidity and mortality. To quantitatively study this edema, we have devised a noninvasive method called Dichromatic Absorptiometry (DA) which is precise (2-3%) and accurate (r equal to 0.99) in measuring changes in tissue fluid. A scanning technique using a

The effect of immediate and delayed cold immersion on burn edema formation and resorption.

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Massive wound edema after a burn may impair healing and help to convert partial to full-thickness injury. Cold treatment (usually by immersion) has been reported to decrease wound edema and is useful in first-aid treatment of burns. Reliable quantitative data have been lacking and frequently a

Direct current reduces wound edema after full-thickness burn injury in rats.

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OBJECTIVE To observe the effect of 4 and 40 microA direct current (DC) on edema formation after burn injury in rats. METHODS Silver-nylon wound dressings were used as either anodes (-) or cathodes (+) on 20% total body surface area full-thickness scalds in anesthetized male Sprague-Dawley rats.

Acute effects of local cold therapy in superficial burns on pain, in vivo microcirculation, edema formation and histomorphology.

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BACKGROUND Local cold therapy for burns is generally recommended to relief pain and limit tissue damage, however, there is limited data of its physiological benefit. This study aimed to evaluate pathophysiological effects of cold therapy in superficial burn on microcirculation, edema formation, and

Increased vascular pedicle width preceding burn-related pulmonary edema.

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Widening of the vascular pedicle on the chest roentgenogram is a recently identified sign of increased circulating blood volume. To determine whether vascular pedicle enlargement can be detected during the initial day of burn resuscitation and whether this change correlates with the early

Early lung dysfunction after major burns: role of edema and vasoactive mediators.

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We determined the effect of a body burn on pulmonary function. Full-thickness burns varying in size from 25 to 70% of total body surface (TBS), were produced in sheep. Resuscitation was performed with lactated Ringer's. We noted an increase in lung transvascular fluid flux as measured by lymph flow,

The reliability and concurrent validity of the figure-of-eight method of measuring hand edema in patients with burns.

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OBJECTIVE Water volumetry is considered the "gold standard" for hand edema assessment. This technique requires considerable time, staff, and specialized equipment. The figure-of-eight method for hand edema assessment has been tested only in the orthopedic population. The objective of this study was

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