cancer pain/blødning

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[Non-opioid analgesics--irreplaceable in cancer pain therapy?

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Sufficient therapy of pain is essential for the treatment of tumor patients. World Health Organisation (WHO)-guidelines recommend a combination of opioids with non-opioid-analgesics (NOA) for patients with medium to strong pain. Cancer pain is often a combination of pain caused by the tumor itself,

Intravenous flurbiprofen axetil can increase analgesic effect in refractory cancer pain.

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BACKGROUND The aim of this study was to investigate the analgesic effects of intravenous flurbiprofen axetil for the refractory pain in cancer patients. METHODS 2109 patients were screened from the department of medical oncology, the first affiliated hospital of Anhui medical university in China

Epidural opiates and local anesthetics for the management of cancer pain.

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The role of epidural morphine in chronic cancer pain treatment is unresolved. In a population of 1205 cancer patients, the aggressive use of systemic opiates limited the trial of epidural analgesia to 16 cases. Successful analgesia was achieved with epidural morphine alone in 6 of these 16 cases

Electrostimulation and neurosurgical measures in cancer pain.

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Neurosurgery for cancer pain may always be considered when the pain no longer responds to conservative treatment methods or only at the cost of undesirable side-effects. Almost all these operations that can be considered for the cancer patient can be performed percutaneously, without general

Alleviating visceral cancer pain in patients with pancreatic cancer using cryoablation and celiac plexus block.

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Little is known about the effects of pancreas cryoablation (PCA) on abdominalgia in pancreatic cancer patients or its synergism with celiac plexus block (CPB). In patients without abdominalgia, to investigate the effects of PCA; in patients with abdominalgia, to investigate the pain-alleviating

Long-term, open catheterization of the spinal subarachnoid space for continuous infusion of narcotic and bupivacaine in patients with "refractory" cancer pain. A technique of catheterization and its problems and complications.

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The technique of long-term, open catheterization of the spinal subarachnoid space for infusion of analgesics in patients with refractory cancer pain is sparsely reported in the literature. We report on a technique using 18G Portex nylon catheters and 16G-17G Tuohy needles, and its problems and

Palliative radiotherapy produced spectacular improvement in a terminally ill colorectal carcinoma patient with severe pain and duodenal bleeding

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Colorectal cancer (CRC) has a devastating effect on the quality of life, and the treatment of active intestinal bleeding in CRC is a real challenge at the end of life. This case report presents a spectacular effect of an unusual palliative treatment strategy in a middle-aged home hospice patient

Serious complications associated with external intrathecal catheters used in cancer pain patients: a systematic review and meta-analysis.

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BACKGROUND Potential risks of intrathecal catheters in cancer patients include infection, bleeding, and neurologic injury. METHODS A systematic review and a pooled analysis of observational studies were performed. Articles reporting on adverse events (infections, bleeding, granuloma, and death)

Double-blind evaluation of short-term analgesic efficacy of orally administered dexketoprofen trometamol and ketorolac in bone cancer pain.

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The analgesic efficacy and safety of dexketoprofen trometamol (the active enantiomer of the racemic compound ketoprofen) (25mg q.i.d.) vs. ketorolac (10mg q.i.d.) was assessed in 115 patients with bone cancer pain included in a multicenter, randomized, double-blind, parallel group study. A level of

Complications after intrathecal drug delivery due to the underlying malignancy in two patients with intractable cancer pain.

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Intrathecal drug delivery is a mode of analgesic delivery that can be considered in those experiencing both refractory pain and excessive side effects from opioid and adjuvant analgesic use. Delivery of analgesic agents directly to the cerebral spinal fluid allows binding of the drug to receptors at

Transdermal fentanyl for cancer pain.

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BACKGROUND Opioid drugs have been used for many years to relieve pain. Transdermal fentanyl offers one option for delivering and maintaining pain relief in patients with moderate or severe cancer pain. OBJECTIVE To determine the analgesic efficacy of transdermal fentanyl for relief of cancer pain,

Clinical analysis of electroacupuncture and multiple acupoint stimulation in relieving cancer pain in patients with advanced hepatocellular carcinoma.

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UNASSIGNED The objective of this study is to investigate the clinical efficacy and safety of electroacupuncture and multiple acupoint stimulation in relieving cancer pain in patients with advanced hepatocellular carcinoma. UNASSIGNED Sixty-five cases of advanced hepatocellular carcinoma with cancer

The role of rofecoxib, a cyclooxygenase-2-specific inhibitor, for the treatment of non-cancer pain: a review.

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Rofecoxib was the first specific inhibitor of cyclooxygenase-2 (COX-2) approved for the treatment of acute pain. It has been shown to provide analgesia that is significantly better than placebo and has an onset of action and efficacy similar to that of traditional nonselective nonsteroidal

Use of ketorolac by continuous subcutaneous infusion for the control of cancer-related pain.

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Ketorolac tromethamine is a newly available non-steroidal anti-inflammatory drug which is suitable for parenteral administration. We have given it by continuous subcutaneous infusion to 36 patients with pain due to advanced cancer. Improvement in pain control occurred in 29 (80%). A reduction in the

Use of the subcutaneous route for the administration of narcotics in patients with cancer pain.

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From February 1985 until January 1987, 108 consecutive patients with pain due to advanced cancer requiring parenteral narcotics were treated with a subcutaneous infusion of morphine (62 patients) or hydromorphone (46 patients). Mean maximal daily dose of morphine and hydromorphone was 305 mg (range,

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