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Receptor mechanism and antiemetic activity of structurally-diverse cannabinoids against radiation-induced emesis in the least shrew.

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Xenobiotic cannabinoid CB1/CB2-receptor agonists appear to possess broad-spectrum antiemetic activity since they prevent vomiting produced by a variety of emetic stimuli including the chemotherapeutic agent cisplatin, serotonin 5-HT3-receptor agonists, dopamine D2/D3-receptor agonists and morphine,

[Review of cannabinoids in the treatment of nausea and vomiting].

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Cannabinoids are used to treat nausea and vomiting. The effect appears to be mediated by cannabinoid receptors in the nucleus tractus solitarius. Results are available from studies on the use of cannabinoids to manage nausea and vomiting after chemotherapy. None of these studies, however, compared

Prevalence of cannabis use has significantly increased in patients with cyclic vomiting syndrome.

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Cyclic vomiting syndrome (CVS) is a functional gastrointestinal disorder which leads to multiple hospitalizations and causes significant impairment of quality of life. Cannabis use is common in patients with CVS, and there are limited data on the national trends in the prevalence of

Burden of Comorbidities in Hospitalizations for Cannabis Use-associated Intractable Vomiting during Post-legalization Period.

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Objective The aim of this study was to observe the trends of intractable vomiting and cannabis use disorder (CUD) with demographic characteristics, medical and psychiatric comorbidities, and hospitalization outcomes. Methods We conducted a retrospective cohort study using the nationwide inpatient

Cannabinoid hyperemesis syndrome: an important differential diagnosis of persistent unexplained vomiting.

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BACKGROUND Chronic nausea and vomiting have a detrimental impact on quality of life. When standard diagnostic investigations fail to provide a definitive diagnosis, patients are often attributed as having a functional gastrointestinal disorder such as cyclic vomiting syndrome. Cannabinoid

Depression, young age, chronic marijuana use, and interepisodic symptoms predict psychological distress in patients with cyclic vomiting syndrome.

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BACKGROUND Cyclic vomiting syndrome (CVS) is often triggered by stress. Patients report high degrees of psychological distress due to CVS, but there is limited data on factors associated with psychological distress. We sought to determine the degree of psychological distress and its correlation with

An Internet survey of marijuana and hot shower use in adults with cyclic vomiting syndrome (CVS).

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Cyclic vomiting syndrome (CVS) is a chronic disorder characterized by episodic nausea and vomiting. A large proportion of patients use marijuana to control their symptoms. Several case reports implicate marijuana as a cause of intractable vomiting with compulsive hot water bathing considered

[Cannabinoid hyperemesis syndrome should be considered by recurrent vomiting].

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Cannabinoid hyperemesis syndrome (CHS) is characterised by unrelenting nausea, recurrent vomiting, abdominal pain and compulsive, hot bathing behaviour. The symptoms contrast the traditional effects associated with cannabis use. We report a "textbook example" of a 26-year-old man with CHS. CHS is an

Association of marijuana use and cyclic vomiting syndrome.

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Cannabis use has become one of the most commonly abused drugs in the world. It is estimated that each year 2.6 million individuals in the USA become new users and most are younger than 19 years of age. Reports describe marijuana use as high as 40-50% in male Cyclic Vomiting Syndrome patients. It is

Cannabinoid hyperemesis syndrome: a cause of refractory nausea and vomiting in pregnancy.

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BACKGROUND Cannabinoid hyperemesis syndrome is a condition present among chronic cannabis users resulting in abdominal pain, intractable nausea and vomiting, and compulsive bathing behaviors. Given the recent legalization of marijuana in certain areas of the United States, the incidence of this

Cannabinoid hyperemesis syndrome as the underlying cause of intractable nausea and vomiting.

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Recently, reports have suggested that chronic cannabis abuse can result in cyclical vomiting, or cannabinoid hyperemesis syndrome. With the increasing prevalence of cannabis use in the United States, this syndrome may be encountered in the emergency department. The authors describe a case of a

Effects of the 2009 Medical Cannabinoid Legalization Policy on Hospital Use for Cannabinoid Dependency and Persistent Vomiting.

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OBJECTIVE In 2009, the U.S. Department of Justice issued a memo stating that it would not prosecute users and sellers who complied with the state laws allowing for medical use of marijuana. There are growing concerns about legalization of marijuana use and its related public health effects. We

Cannabinoid Hyper-emesis Syndrome: An Enigma.

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Marijuana is one of the most frequently abused illicit substances in the world especially Australia. Cannabinoid Hyperemesis Syndrome (CHS) is characterized by a triad of symptoms: Cyclic vomiting, chronic marijuana use, and compulsive bathing. It involves recurrent episodes of self-limited nausea

[Cannabinoid hyperemesis syndrome causing prolonged nausea and vomiting in patients with cannabis abuse].

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Cannabis is one of the most used drugs worldwide. The link between repeated episodes of nausea, vomiting, and cannabis abuse is often missed in patients with prolonged cannabis abuse and is named cannabinoid hyperemesis syndrome. Characteristically, the symptoms appear in a cyclical pattern and are

Psychogenic vomiting complicated by marijuana abuse and spontaneous pneumomediastinum.

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OBJECTIVE This case illustrates an unusual physical sequel of psychogenic vomiting. METHODS A 22-year-old man with a picture of psychogenic vomiting and marijuana use developed the complications of a pneumomediastinum and subcutaneous emphysema. METHODS Therapy included gradual exposure to anxiety

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