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capsaicin/atrofi

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Small fiber neuropathy (SFN) is a type of peripheral neuropathy that affects the small unmyelinated fibers, including both somatic innervation of the skin and autonomic nerves. Although diabetes and prediabetes are the two most common causes, up to 50% of all SFN remain idiopathic. Currently there

Efficacy of Subcutaneous Injection of Etanercept for Moderate and Severe Knee Osteoarthritis

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1. Background: Osteoarthritis (osteoarthritis, OA) is a common joint disease. It is characterized by recurrent joint pain, swelling, increasing of disease status, joint deformity and activity disorders. The pathogenesis of OA has not been fully understood. It may be associated with a variety of

Efficacy of Intra-Articular Injection of Etanercept for Moderate and Severe Knee Osteoarthritis

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1. Background: Osteoarthritis (osteoarthritis, OA) is a common joint disease. It is characterized by recurrent joint pain, swelling, increasing of disease status, joint deformity and activity disorders. [1] The pathogenesis of OA has not been fully understood. It may be associated with a variety of

Autofluorescent Flavoprotein Imaging of Intraepidermal Nerve Fibers: a Pilot Study

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The first aim of the current project is to test the precision of AFI in the epidermis of 10 healthy volunteers. For this purpose, a range of nociceptive electrical stimuli with increasing intensities (5Hz @ 0.5mA-1.0mA) and one innocuous control stimulus (2000Hz @1mA) will be delivered to the third

Neuro-immunological Analysis of Idiopathic Rhinitis Patients and Controls Treated With Capsaicin.

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The Effect of High-dose Remifentanil on Established Capsaicin-induced Hyperalgesia in Human Volunteers

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The Effect of Remifentanil on Established Capsaicin-Induced Hyperalgesia in Human Volunteers

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In Vitro Studies on Pharmacological Regulation and Genetic Risk Factors of Peripheral Human Nociceptors

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Purpose/Objectives a. Specific Aims Specific Aim 1: Characterize in humans the effects of inflammation and neuronal degeneration on peripheral levels of NPY, and related Y receptors (Y1, Y2, Y5) in periradicular tissue. Specific Aim 2: Determine whether NPY inhibits neurosecretion from peripheral
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