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Natural products with bioactive components are widely studied on various cancer cell lines for their possible cytotoxic effects, recently. Among these products, honey stands out as a valuable bee product containing many active phenolic compounds and flavonoids. Numerous types of multifloral honey
OBJECTIVE Defects in the homologous recombination (HR) DNA repair pathway sensitize tumors to therapeutics that target this pathway. A significant proportion of triple-negative breast cancers (TNBC) carry HR defects. The HRD assay is highly associated with sensitivity to neoadjuvant platinum-based
Preoperative breast MRI does not decrease re-excision rates in patients who undergo lumpectomy. We evaluated concordance of tumor size on MRI and pathologic size in patients who underwent re-excision of margins after lumpectomy. A retrospective review of patients at the Cedars-Sinai Breast Center
In this paper, we present a novel approach of implementing a combination methodology to find appropriate neural network architecture and weights using an evolutionary least square based algorithm (GALS).1 This paper focuses on aspects such as the heuristics of updating weights using an evolutionary

Prevalence of BRCA1 and BRCA2 germ line mutations among women with carcinoma of the fallopian tube.

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OBJECTIVE The purpose of this study is to determine the prevalence of BRCA1 and BRCA2 mutations among a large series of women with carcinoma of the fallopian tube. METHODS Two series of women diagnosed with carcinoma of the fallopian tube were studied. Women identified from the Ontario Cancer
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