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chemotherapy/diarré
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Methods of treating chemotherapy-induced diarrhea/mucositis using glucagon-like-peptide-2(GLP-2)analogues
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FIELD OF THE INVENTION
The present invention relates to glucagon-like-peptide-2 (GLP-2) analogues and their medical use, for example in the prophylaxis or treatment of stomach and bowel-related disorders and for ameliorating side effects of chemotherapy and radiation therapy.
BACKGROUND OF THE
Method for treating acute and severe diarrhea
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FIELD OF THE INVENTION
The present invention relates generally to a method for treating acute and severe diarrhea as may occur during chemotherapy or acute narcotic withdrawal. More particularly, the present invention provides such a method utilizing the somatostatin analogue octreotide.
BACKGROUND
Methods of treating a gastrointestinal spasm associated with chemotherapy or radiation therapy
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BACKGROUND
1. Field of the Invention
The teachings provided herein relate to methods of treating a gastrointestinal spasms associated with chemotherapy or radiation therapy.
2. Description of Related Art
Antispasmodics can be used to prevent spasms of the stomach, intestine, uterus, or urinary
Method for treating acute and severe diarrhea
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FIELD OF THE INVENTION
The present invention relates generally to a method for treating acute and severe diarrhea as may occur during chemotherapy or acute narcotic withdrawal. More particularly, the present invention provides such a method utilizing the somatostatin analogue octreotide.
BACKGROUND
Imidazolyl derivatives
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BACKGROUND OF THE INVENTION
The present invention is directed to compounds and compositions containing said compounds which bind selectively to somatostatin receptor subtypes and the use of said compounds for treating medical disorders which are mediated by somatostatin receptor subtypes.
Compositions and methods for selectively inhibiting intestinal carboxylesterase 2 enzyme activity
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BACKGROUND
Camptothecin (CPT)-derived drugs, such as irinotecan (CPT-11), are typically used for treating solid brain, colon, and lung tumors, as well as for treating refractory forms of leukemia and lymphoma. See Pommier Nat. Rev. Cancer, 6(10):789 802.
The antineoplastic efficacy of CPT-11 is
Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists
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FIELD OF INVENTION
The present invention is directed to modulators of the TGR5 receptor useful in the treatment of TGR5 mediated diseases or disorders. Specifically, the invention is concerned with compounds and compositions thereof, which activate the TGR5 receptor, methods of treating diseases or
Method of using a gastrointestinal stimulator device for digestive and eating disorders
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BACKGROUND OF THE INVENTION
Gastrointestinal stimulation, or pacing, was advocated as a possible treatment for gastric motor dysfunction as early as 1963. Experimentation in the late 1960s and early 1970s, began to demonstrate the significance of gastrointestinal myoelectrical activity and its
Polymorphic crystalline forms of tiacumicin B
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2. FIELD OF THE INVENTION
The invention encompasses novel forms of compounds displaying broad spectrum antibiotic activity, especially crystalline polymorphic forms and amorphous forms of such compounds, compositions comprising such crystalline polymorphic forms and amorphous forms of such
Macrocyclic polymorphs, compositions comprising such polymorphs and methods of use and manufacture thereof
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2. FIELD OF THE INVENTION
The invention encompasses novel forms of compounds displaying broad spectrum antibiotic activity, especially crystalline polymorphic forms and amorphous forms of such compounds, compositions comprising such crystalline polymorphic forms and amorphous forms of such
Macrolide polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof
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2. FIELD OF THE INVENTION
The invention encompasses novel forms of compounds displaying broad spectrum antibiotic activity, especially crystalline polymorphic forms and amorphous forms of such compounds, compositions comprising such crystalline polymorphic forms and amorphous forms of such
Macrocyclic polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof
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2. FIELD OF THE INVENTION
The invention encompasses novel forms of compounds displaying broad spectrum antibiotic activity, especially crystalline polymorphic forms and amorphous forms of such compounds, compositions comprising such crystalline polymorphic forms and amorphous forms of such
Macrolide polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof
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2. FIELD OF THE INVENTION
The invention encompasses novel forms of compounds displaying broad spectrum antibiotic activity, especially crystalline polymorphic forms and amorphous forms of such compounds, compositions comprising such crystalline polymorphic forms and amorphous forms of such
Benzimidazolone derivatives as CB2 receptor ligands
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BACKGROUND OF THE INVENTION
This invention relates to benzimidazolone derivatives. These compounds have selective cannabinoid(CB)2 receptor binding activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the
Sulfonyl benzimidazole derivatives
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BACKGROUND OF THE INVENTION
This invention relates to sulfonyl benzimidazole derivatives. These compounds have selective cannabinoid (CB)2 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives
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