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Suloexide in the Treatment of Early Stages of COVID-19
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Objective:
To use sulodexide in patients that have early onset of COVID-19 symptoms to mitigate the progression of the disease process that can allow them to recover at home, and limit the need for hospital care and the more severe manifestation which includes fulminant respiratory failure, acute
Methotrexate Versus Secukinumab Safety in Psoriasis Patients With Metabolic Syndrome
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A prospective, non-randomized controlled open trial in psoriasis patients with metabolic syndrome was conducted between January 2019 and May 2020. Inclusion criteria were age ≥ 18 years, being affected by moderate to severe chronic plaque psoriasis and concomitant metabolic syndrome and being
Northeast COVID-19 and Pregnancy Study Group
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General Objective: To determine the frequency of COVID-19 in pregnant and postpartum women admitted with flu syndrome, to evaluate the clinical and laboratory predictors of COVID-19 progression and to identify the factors associated with adverse maternal and perinatal / neonatal outcomes in six
Longitudinal Follow-up Study in Two Chinese Hypertension Cohorts
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This study is a longitudinal cohort follow-up study. The main contents include:
(1) Questionnaire design: the questionnaire is designed according to the research contents and purposes. The standard questionnaires will be used to collect the general information, dietary habits, lifestyle, medical
Epicardial Fat Thickness and Inflammation in People With Metabolic Syndrome and Obesity
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Epicardial adipose tissue (EAT) is a kind of VAT, between the surface of the myocardium and the epicardium. It can easily be measured by standard two-dimensional (2D) echocardiography. EAT serves as an endocrin organ that secretes hormones, inflammatory citokins and chemokines. Previous data
Relation Between Plasma Apelin Level and Diabetic Nephropathy in Type 2 Diabetes Patients.
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Introduction Type 2 Diabetes Mellitus is a metabolic syndrome associated with hyperglycemia due to defect in secretion or action of insulin or both. Long term hyperglycemia leads to complications of microvasculature involving the eyes, kidneys and nerves.
Diabetic nephropathy (DN) is the commonest
Randomized Double Blind Placebo Controlled Clinical Trial to Evaluate Obese and Overweight Subjects
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The primary objective of the study is to evaluate the effect on weight loss in a group of subjects suffering from overweight and mild obesity (BMI between 25 and 32 Kg/m2) and with weight > 75 Kg/m2 being administered with a 3 g/day polyglucosamine dosage.
The secondary objectives of the study
COVID-EC Study: Clinical Characteristics of Patients With COVID-19 in Guayaquil, Ecuador
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Design: Retrospective cohort study that will review the data of patients seen in participating centers with a confirmed or probable diagnosis of COVID-19 between March and April 2020. Those patients who test positive for nasopharyngeal exudate for SARS-CoV-2 will be considered a confirmed case using
Metformin in Dengue With Obesity
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This is an open-label safety and tolerability study investigating the effects of five days of metformin treatment. The metformin therapy will be given to eligible participants admitted to the Hospital for Tropical Diseases (HTD) in Ho Chi Minh City, Vietnam. The 60 patients receiving metformin
Safety and Efficacy of Ketogenic Diet for Promoting Weight Loss in Obese Individuals With Compensated NASH Cirrhosis
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The primary aim is to assess the safety of ketogenic diet as compared to standard of care approach for weight loss in patients with compensated cirrhosis due to NASH. The safety endpoints captured in the study include liver decompensation events, measured through several questionnaires, fasting
Prognostic Factors Keeping Track for COVID-19 Pneumonia
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It has been reported that nearly half of the patients who are hospitalized for Covid-19 pneumonia have on admission old age or comorbidities.
In particular, hypertension was present in 30% of the cases, diabetes in 19%, coronary heart disease in 8% and chronic obstructive lung disease in 3% of the
Effects of Hydroxytyrosol Administration in Anthropometric Parameters in Overweight and Obese Women
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Hydroxytyrosol is an extra virgin olive oil phenolic compound which has known protective effects in LDL oxidation and reduces oxidative stress. Olive oil has been associated with enhanced weight loss, and hydroxytyrosol could have a potential role in this.
Participants entered the study after
Reversibility of Brain Glucose Transport and Metabolism in T2DM: an Intervention Study
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Specific Aim 1: To compare brain glucose transport and metabolism in age, BMI, and HbA1c matched T2DM individuals with either long duration of diabetes or short duration of diabetes using brain 1H MRSI during hyperglycemic clamp
Hypothesis: T2DM individuals with chronic uncontrolled diabetes will
Kidney Affection in Non Alcaholic Fatty Liver Diseases
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With the increasing prevalence of obesity, diabetes mellitus and the metabolic syndrome in the general population, non-alcoholic fatty liver disease (NAFLD) has become the most common cause of chronic liver disease. NAFLD refers to a wide spectrum of liver damage, ranging from simple steatosis to
Effect of Automatic Recruitment Maneuver on Peroperative Lung Mechanics of Obese Laparoscopic Abdominal Surgery Patients
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