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Role of Montelukast in Modulation of Response to Sepsis in Preterm Infants

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Since inflammatory mediators play a crucial role in the pathophysiology of sepsis so anti-inflammatory treatment, Montelukast, could be a beneficial therapy. The investigators will conduct this pilot, open-labeled, randomized controlled intervention trial on 40 newborns admitted to NICU. The study
PRIMARY OBJECTIVE: I. To determine if treatment with lopinavir/ritonavir will decrease progression of symptoms compared to control/placebo. SECONDARY OBJECTIVES: I. Determine if treatment improves time to symptom resolution. II. Determine the time to symptom progression. III. Determine time to

The Effect of Diabetes Mellitus in Colonoscopy Under Sedoanalgesia

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Effects of Endothelin Receptor Antagonist on Ischemic Kidney Injury During Nephron Sparing Surgery

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This is a study aimed at examining the protective effect of endothelin antagonism on the ischemic damage the kidney undergoes during partial nephrectomy for kidney lesion removal. In such procedure, it is common to clamp the kidney blood vessels in order to eliminate blood flow in the surgical field

Northeast COVID-19 and Pregnancy Study Group

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General Objective: To determine the frequency of COVID-19 in pregnant and postpartum women admitted with flu syndrome, to evaluate the clinical and laboratory predictors of COVID-19 progression and to identify the factors associated with adverse maternal and perinatal / neonatal outcomes in six

Does Omission of NSAIDs After Colorectal Cancer Operation Affect the Consumption of Opioids?

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Background: Many standard analgesic regimens after colorectal cancer surgery includes a NSAID in combination with paracetamol and other non-opioid analgesics. Concerns about a risk of cardiovascular and renal impairment and the possible association with anastomotic leaks have questioned the

Effects a Honey Based Syrup on Blood Parameters in Patients With Breast Cancer

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Women patients with breast cancer referring to Shohaday-e- Tajrish Hospital of Tehran who are under chemotherapy treatment. In order to blind the investigator, medications are named as "A" for syrup of HB and B for placebo. The patients don't aware of the type of drug they are assigned to. In

Administration of Allogenic UC-MSCs as Adjuvant Therapy for Critically-Ill COVID-19 Patients

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This study is a double blind, randomized control trial (RCT). This study will be concluded in 2 months, from May to July 2020, from subject selection to the end of follow up. Research subjects are obtained consecutively from Covid-19 patients who receive care in the intensive care unit (ICU) across

Covid-19: Possible Role of Neutrophil Extracellular Traps

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The process by which neutrophils expel DNA together with various proteins to the outside, forming a network structure called Neutrophil Extracellular Traps (NETs) constitutes a particular cell death that involves the destruction of the nuclear membrane before the plasmatic one. This process is

The Effect of Berberine on Intestinal Function and Inflammatory Mediators in Severe Patients With Covid-19

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Patients aged 18-80 years who confirmed with COVID-19 and classified as severe were enrolled in the study, and then separated randomly into two groups: a berberine group (B group) and a control group (C group). The diagnostic criteria for severe cases are in accordance with the Diagnosis and

Investigating the Role of Vitamin D in the Morbidity of COVID-19 Patients

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STUDY DESIGN Arm 1: Hospital in-patients with a clinical diagnosis of COVID-19 This will be an observational cohort study of patients hospitalised at Tameside General Hospital with a clinical diagnosis of COVID-19, as defined by the clinical coding department. Patient identifiers will be extracted
The study is a prospective, multi-center, randomized, placebo-controlled study. The ethical committee of the Faculty of Medicine, Assiut University approved the study protocol. 200 diabetic patients with indication for coronary intervention participated in the study. 100 patients were randomly

Protective Effect of Aspirin on COVID-19 Patients

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1. COVID-19 has a high infection rate and mortality, and serious complications such as heart injury cannot be ignored. At present, the scale and harm of COVID 19 (Novel coronavirus pneumonia (NCP) has far surpassed that of SARS in 2003, with more than 80,000 cases confirmed in China and 3,119 deaths

National Survey of Symptoms of People Aged 70 and Overs Diagnosed With COVID-19

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This cross-sectional survey was initiated and conducted by the French Society of Geriatrics and Gerontology. A standardized questionnaire was emailed to 1600 geriatrician members of the French Society of Geriatrics and Gerontology throughout France between March 22, 2020 and April 5, 2020.
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