Supplementation of 3.7 g of docosahexanoic and eicosapentanoic acids per day during 12 weeks

Supplementation of 3.7 g of corn oil per day during 12 weeks

Supplementation of 3.7 g of docosahexanoic and eicosapentanoic acids per day during 12 weeks
Omega 3 fatty acids: Omega 3 fatty acids will be provided in a dose of 3.7 g/day, that should be enough to rise red blood cell levels of eicosapentanoic and docosahexanoic acids

Omega 3 Fatty Acids

Supplementation of 3.7 g of corn oil per day during 12 weeks
Corn oil: Corn oil will be the placebo comparator for omega 3 fatty acids supplement

Corn Oil

Total

Sex: Female, Male

Ethnicity (NIH/OMB)

Region of Enrollment

Urine albumin excretion

Number of participants in whom urine albumin excretion in a spot urine sample at the end of follow up, expressed as mg/g creatinine, decreased by 20% or more

Number of Participants With a Urine Albumin Excretion Decrease of 20% or More

Blood C reactive protein measured at baseline and the end of the intervention.

Change in C Reactive Protein Levels at 12 Weeks of Intervention

Measurement of pulse wave velocity using a oscillometric device measured at baseline and end of follow up and expressed ad m/s

Change in Pulse Wave Velocity at 12 Weeks of Intervention

Overall Study

Dr. Francisco Perez Bravo, Director

Renal Insufficiency, Chronic

Omega 3 fatty acids will be provided in a dose of 3.7 g/day, that should be enough to rise red blood cell levels of eicosapentanoic and docosahexanoic acids

Omega 3 fatty acids

Corn oil will be the placebo comparator for omega 3 fatty acids supplement

Corn oil

Institute of Nutrition and Food Technology University of Chile

Omega 3 Fatty Acids in Patients With Chronic Renal Disease

Effects of the Supplementation With Omega 3 Fatty Acids in Patients With Chronic Renal Disease

Sharing of information must be discussed with the sponsor

Daniel Bunout

Full profesor

University of Chile

Servicio de Salud Metropolitano Oriente

Participants will be randomly selected to receive 3.7 g of a supplement containing docosahexanoic and eicosapentanoic acids or a supplement containing corn oil. The supplements will be provided for 12 weeks

Identical sachets containind the study supplement or corn oil will be number coded and provided to participants

creatinine/majs

Omega 3 Fatty Acids in Patients With Chronic Renal Disease

Management of Hyponatremia in Preterm Infants on Diuretics

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