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SURgical Outcomes in COvid Patients - the SUROCO Multicenter Cohort Study (COVID-19)
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METHODS Objectives
Primary: To describe the observed surgical needs of COVID-19 patients in Canadian centers.
Secondary: To measure the association between preoperative characteristics and postoperative outcomes in COVID-19 patients.
Tertiary: To quantify the operating room workload and modified
Does Omission of NSAIDs After Colorectal Cancer Operation Affect the Consumption of Opioids?
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Background:
Many standard analgesic regimens after colorectal cancer surgery includes a NSAID in combination with paracetamol and other non-opioid analgesics. Concerns about a risk of cardiovascular and renal impairment and the possible association with anastomotic leaks have questioned the
Eliquis Acute Stroke Safety Evaluation
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Study Hypothesis:
Investigators hypothesize that early initiation of apixaban within the first 14 days of stroke or TIA is not associated with increased symptomatic intracranial haemorrhage.
Study Design:
EASSE is an investigator-initiated prospective, open label, single arm phase IV study.
Phenotyping Individuals With Neo-diagnosed Type 2 Diabetes at Risk for All-cause Mortality
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Patients referring for the first time to the outpatient diabetes clinic in the department of Internal Medicine between January 2008 and December 2015 and matching the inclusion criteria were recruited.
Diagnosis was confirmed on the basis of the Oral Glucose Tolerance Test (OGTT) or HbA1c ≥6.5% plus
Intracorporeal Nanocomposites and Neurological Disorders in Fulgurates (FulgurnanoF)
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In order to detect nanocomposites in patients who have been impacted by lightning, an analysis protocol will be performed on the remains of blood and urine samples from their initial medical admission. After filtering the blood and urine samples, the remaining nanocomposites are selected for
Role of Sacubitril/Valsartan in the Improvement of Heart Failure With Reduced Ejection Fraction
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Therapeutic interventions were made according to a titration protocol in stable optimal medical therapy. Therapy with sacubitril/valsartan was introduced after a 48-hour wash-out of an ACE inhibitor or after a 24-hour wash-out of an angiotensin receptor antagonist. Doses of sacubitril/valsartan were
Ultrasonography for Fluid Assessment in Parturients With Preeclampsia Undergoing Cesarean Section
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Fluid resuscitation is a key determinant in the management of these parturients. Hypovolemia exacerbates organ failure, whereas volume overload results in pulmonary edema. In this setting, the use of noninvasive hemodynamic monitoring is associated with reduced mortality.
Point-of-care lung
COVID-EC Study: Clinical Characteristics of Patients With COVID-19 in Guayaquil, Ecuador
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Design: Retrospective cohort study that will review the data of patients seen in participating centers with a confirmed or probable diagnosis of COVID-19 between March and April 2020. Those patients who test positive for nasopharyngeal exudate for SARS-CoV-2 will be considered a confirmed case using
Cardiovascular and Renal Biomarkers to Predict Acute Heart or Kidney Injury in Severe Covid-19 Infection
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Secondary objectives
Evaluate the association of the concentrations at inclusion AND of the variations (between inclusion and 72H post-inclusion) of blood and urine cardiovascular-renal biomarkers of interest (selected a priori: cardiac (NT-proBNP, (bio)-Adrenomedullin), coagulation (D-dimers),
CCM Italian Registry
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Introduction The Cardiac Contractility Modulation (CCM) system is a cardiac implantable device indicated for the treatment of patients with symptomatic heart failure with left ventricular systolic dysfunction despite optimal medical and electrical therapy.
This system consists of a generator to
Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients
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The Takayasu arteritis (TAK) is a rare chronic inflammatory arteritis, which lacks effective well-accepted intervention strategy. Previous studies have revealed that methoxamine, tofacitinib, adalimumab, and tocilizumab were effective in controlling disease activity and preventing disease relapse in
A Pilot Study in Severe Patients With Takayasu Arteritis.
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The Takayasu arteritis (TAK) is a rare chronic inflammatory arteritis, which lacks an effective well-accepted intervention strategy. Previous studies have revealed that methotrexate, tofacitinib, adalimumab, and tocilizumab were effective in controlling disease activity and preventing disease
Effect of High Protein Diet in Stroke Patients With Low Muscle Mass
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Comparison of Fibrinogen Concentrate and Cryoprecipitate in Pediatric Cardiac Surgery Patients
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Once the need for fibrinogen supplementation is confirmed, study participants will be randomized into one of two treatment groups (n=15 in each group):
1. Cryoprecipitate group (dose: 10 ml/kg; active control group) or
2. Fibrinogen Concentrate group (dose: 70 mg/kg; intervention group). There will
Ultra-high-resolution CT vs. Conventional Angiography for Detecting Coronary Heart Disease
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Primary Objective The primary objective of this study is to generate preliminary data in support of the hypothesis that noninvasive UHR-CT is not inferior to invasive coronary angiography by cardiac catheterization for identifying patients with hemodynamically significant CHD.
Secondary Objectives
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