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early/baktericider
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Early and extended early bactericidal activity of linezolid in pulmonary tuberculosis.
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BACKGROUND
Linezolid, the first oxazolidinone approved for clinical use, has effective in vitro and promising in vivo activity against Mycobacterium tuberculosis.
OBJECTIVE
To evaluate the early and extended early bactericidal activity of linezolid in patients with pulmonary
Early and extended early bactericidal activity of levofloxacin, gatifloxacin and moxifloxacin in pulmonary tuberculosis.
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OBJECTIVE
To evaluate the early bactericidal activity (EBA) of the new fluoroquinolones levofloxacin, gatifloxacin and moxifloxacin in patients with pulmonary tuberculosis (PTB).
METHODS
Randomized, open-label trial. Forty adults with newly diagnosed smear-positive PTB (10 per arm) were assigned to
The early bactericidal activity of streptomycin.
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METHODS
Patients with sputum smear-positive, newly diagnosed pulmonary tuberculosis studied at Tygerburg Hospital, Cape Town, for their early response to streptomycin (SM).
OBJECTIVE
To determine the standard early bactericidal activity (EBA), namely the fall in viable counts of tubercle bacilli in
Early bactericidal activity of antituberculosis agents.
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The early bactericidal activity (EBA) of an antituberculosis agent is arbitrarily defined as the fall in log(10) colony forming units (cfu) of Mycobacterium tuberculosis per ml sputum per day during the first 2 days of treatment. Determining the EBA is an important preliminary step in the clinical
The early bactericidal activity of antituberculosis drugs.
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Early bactericidal activity studies measure the ability of antituberculosis treatments to reduce the burden of Mycobacterium tuberculosis in sputum specimens collected overnight from smear-positive pulmonary tuberculosis patients during the first 14 days of therapy. This confirms the efficacy of
Antibacterial treatment needed for severe early childhood caries.
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OBJECTIVE
To assess the effects of a single 10% povidone iodine application as an adjunct to extensive surgical procedures in the clinical treatment of children with early childhood caries.
METHODS
Twenty-two children scheduled for dental treatment under general anesthesia were randomized into
The early bactericidal activity of anti-tuberculosis agents.
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The early bactericidal activity of amikacin in pulmonary tuberculosis.
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METHODS
Stellenbosch University, a tertiary care hospital in Cape Town, South Africa.
OBJECTIVE
To determine the early bactericidal activity (EBA) of amikacin in dosages of 5 mg/kg, 10 mg/kg and 15 mg/kg body weight in comparison to that of isoniazid 6 mg/kg body weight or no drug.
METHODS
An open,
Early bactericidal activity trial of nitazoxanide for pulmonary tuberculosis.
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SettingThis study was conducted in treatment-naïve adults with drug-susceptible pulmonary tuberculosis in Port-au-Prince, Haiti.ObjectiveTo assess the safety, bactericidal activity and pharmacokinetics of nitazoxanide (NTZ).DesignThis was a prospective phase II clinical trial in 30 adults with
Early bactericidal activity of new drug regimens for tuberculosis.
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Early bactericidal activity of new drug regimens for tuberculosis.
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Early bactericidal activity of new drug regimens for tuberculosis.
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Early bactericidal and sterilizing activities of ciprofloxacin in pulmonary tuberculosis.
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The early bactericidal and sterilizing activities of ciprofloxacin were evaluated in the treatment of adult patients with smear positive pulmonary tuberculosis. Two randomized prospective studies were performed in Northern Tanzania. In study 1, ten patients received either 750 mg ciprofloxacin or
Early Bactericidal Activity of AZD5847 in Patients with Pulmonary Tuberculosis.
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AZD5847 is an oxazolidinone antibiotic with in vitro activity against Mycobacterium tuberculosis The objective of this study was to evaluate the antimycobacterial activity, safety, and pharmacokinetics of AZD5847 in patients with pulmonary tuberculosis. Groups of 15 treatment-naive, sputum
Bactericidal coating to prevent early and delayed implant-related infections
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The occurrence of an implant-associated infection (IAI) with the formation of a persisting bacterial biofilm remains a major risk following orthopedic biomaterial implantation. Yet, progress in the fabrication of tunable and durable implant coatings with sufficient bactericidal activity to prevent
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