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The effect of oxygen deprivation upon UVA-, UVB-, and PUVA-induced pigment and erythema responses in normal human skin was examined. Before exposure, varying degrees of hypoxia in the skin of the forearm were achieved by inflating a sphygmomanometer cuff applied to the upper arm. After the
Indigo carmine (also known as 5,5'-indigodisulfonic acid sodium salt or indigotine) is a blue dye that is administered intravenously to examine the urinary tract and usually is biologically safe and inert. Indigo carmine rarely may cause adverse reactions. We treated a 66-year-old man who had
OBJECTIVE
To assess the effectiveness of high-Dk soft contact lenses with oxygen transmissibility (Dk/L) beyond the critical level required to avoid corneal edema during overnight wear.
METHODS
The most up-to-date data available on clinical signs of hypoxia with high-Dk contact lenses is
OBJECTIVE
The purpose of this article is to review the literature to date to determine if silicone hydrogel lenses have eliminated corneal hypoxia.
METHODS
Results from clinical studies, including short-term laboratory studies and retrospective and prospective clinical trials that have assessed the
BACKGROUND
Rheumatoid arthritis (RA) is an inflammatory articular disease with cartilage and bone damage due to hyperplasic synoviocyte invasion and subsequent matrix protease digestion. Although monoclonal antibodies against tumor necrosis factor alpha (TNFα) have been approved for clinical use in
Emerging evidence indicates that myeloid cells are essential for promoting new blood vessel formation by secreting various angiogenic factors. Given that hypoxia-inducible factor (HIF) is a critical regulator for angiogenesis, we questioned whether HIF in myeloid cells also plays a role in promoting
Significant advances during the past decade in silicone hydrogel lenses have made them the primary mode for new contact lens wear. Their dominance in the market place is driven largely by the elimination of structural and physiological changes induced by contact lens-induced hypoxia, as exemplified
Erythromelalgia is a clinical syndrome characterized by burning pain in the extremities together with erythema and increased skin temperature. Typically, the patients experience relief from cold, and aggravation from warmth. Symptoms are hypothesized to be caused by arteriovenous shunting and
The paper presents the results of a study of embryonic or primitive hemoglobin (HbP), by using the authors' developed immunodiffusion monovalent test system in the neonatal umbilical blood and in girls than in the boys. HbP was also detected in patients with erythema (66.7%) and acute myeloleukemia
We report a 54-year-old patient with the association of hepatic dysfunction with cyanosis, severe hypoxemia, platypnea-orthodeoxia, diffuse cutaneous spider nevi, telangiectasia, palmar erythema, digital clubbing and findings of marked intrapulmonary vascular dilation and arterovenous shunt. The
Liquid laundry detergent capsules contain concentrated liquid laundry detergent in a water-soluble polyvinyl alcohol membrane.To review 4652 exposures reported to the United Kingdom National Poisons Information Service (NPIS) and to assess the impact of In contrast with the past, the water buffalo is now not only a draft animal, but also an important food source of milk and meat. It is increasingly apparent that the water buffalo have huge potential for meat production, but its breeding needs to be investigated. Regarding the molecular mechanisms
OBJECTIVE
To establish the temporal sequence of limbal hyperaemia in humans without contact-lens wear and during conventional and highly oxygen-permeable soft-contact-lens wear.
METHODS
Two, 16-h, non-dispensing clinical studies were conducted, each incorporating 8 h of open eye with normal
Erythromelalgia is characterized by burning pain, erythema, and increased temperature in acral skin. The pain is aggravated by warming and relieved by cooling. Increased microvascular arteriovenous shunting in deep dermal plexa has been hypothesized as the pathogenetic mechanism of pain in affected
BACKGROUND
We describe a patient with a high-titer warm immunoglobulin (Ig)A autoantibody resulting in death due to hemagglutination rather than to hemolysis.
METHODS
A 47-year-old male patient presented with an intriguing pronounced vascular erythema of the skin. A livedo reticularis associated