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ethanolamine/infarkt
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15 resultater
A reappraisal of the dog-heart infarct plasmalogen, its conception as a bis-phosphatidic acid and current recognition as an N-acyl phosphatidyl ethanolamine.
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1. We have re-examined the lipids from myocardial infarcts of cat, dog, rabbit and man, mainly through TLC methods, and confirm the identity of cat and dog "infarct plasmalogen" as an N-acyl phosphatidyl ethanolamine (NAPE). This substance was not detected in infarcts of rabbit and man. 2. We have
Splenic infarction: an unusual complication of ethanolamine oleate injection.
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Ethanolamine is a novel STAT-3 dependent cardioprotective agent.
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Ethanolamine is a biogenic amine found naturally in the body as part of membrane lipids and as a metabolite of the cardioprotective substances, sphingosine-1-phosphate (S1P) and anandamide. In the brain, ethanolamine, formed from the breakdown of anandamide protects against ischaemic apoptosis.
Identification of ethanolamine in rat and gerbil brain tissue extracts by NMR spectroscopy.
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Some NMR resonances which have previously been observed but not identified in mammalian brain tissue extracts have been shown to arise from ethanolamine. This conclusion is drawn from a systematic study of the perchloric acid extracts of rodent brain tissue in which several NMR experiments were used
Plasma cephalins of patients with acute myocardial infarction.
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In the plasma of patients with acute myocardial infarction the values for phosphatidyl ethanolamine are on the average 50% to 100% higher than in patients with chronic coronary heart disease and up to 400% higher than in normal individuals. Those for phosphatidyl serine are about 50% higher than in
[Mechanism of action of sodium oxybutyrate in experimental myocardial infarction].
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Effect of sodium hydroxybutyrate on lipid metabolism was studied in experimental infarction of rabbit myocardium. Administration of 80 mg of sodium hydroxybutyrate per kg of body mass caused a decrease of free fatty acids content in the infarction zone, in surrounding zones and in blood. Treatment
[Lipid spectra of various zones of the myocardium, damaged by infarct, as a reflection of its metabolic and functional activity in the period preceding the lethal outcome of the illness].
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Lipid composition was studied in various zones of the myocardium impaired with infarction. Content of phospholipids was decreased, while lysophospholipids and free fatty acids were increased in the necrosis-impaired sites. In the overinfarction-impaired tissues content of total lipids,
Increased accumulation of PEG-PE micelles in the area of experimental myocardial infarction in rabbits.
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Micelles prepared from polyethyleneglycol/phosphatidyl-ethanolamine conjugates (PEG-PE) with a size of 7-20 nm and zeta-potential of approximately -18 mV were administered i.v. to rabbits with experimental myocardial infarctions. Micelles demonstrated a prolonged circulation in the blood (half-life
Accumulation of N-acylethanolamine glycerophospholipids in infarcted myocardium.
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A new phospholipid was detected in the infarcted areas of canine myocardium 24 h after ligation of the left descending branch of the coronary artery. Both the central and peripheral areas of the infarct contained significant amounts of this lipid (4-6& of lipid phosphorus), but it was not present in
Spinal cord paralysis following sclerotherapy for esophageal varices.
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A child with cryptogenic cirrhosis underwent a third session of elective sclerotherapy. Endoscopic therapy consisted of intravascular injection of ethanolamine oleate in varices newly developed at the midesophagus level. Irreversible paraplegia was documented within 8 hr postoperatively. Two years
UPLC-HRMS-Based Plasma Metabolomic Profiling of Novel Biomarkers by Treatment with KDZI in Cerebral Ischemia Reperfusion Rats.
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Kudiezi injection (KDZI), also known as Diemailing injection, is a traditional Chinese medicine injection of the composite plant Ixeris sonchifolia Hance (also known as Kudiezi), and has been widely used to treat coronary heart disease, angina pectoris, and cerebral infarction, but its
Short-term complications of retrograde transvenous obliteration of gastric varices in patients with portal hypertension: effects of obliteration of major portosystemic shunts.
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The type, incidence, and severity of complications of balloon-occluded retrograde transvenous obliteration (B-RTO) for gastric varices should be precisely estimated. Complications were evaluated in 38 patients who had fundic gastric varices and 43 B-RTO procedures during injection of ethanolamine
Intracellular mechanisms of N-acylethanolamine-mediated neuroprotection in a rat model of stroke.
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N-acyl ethanolamines (NAEs) are endogenous lipids that are synthesized in response to tissue injury, including ischemia and stroke, suggesting they may exhibit neuroprotective properties. We hypothesized that NAE 16:0 (palmitoylethanolamine) is neuroprotective against ischemia-reperfusion injury in
Lipid-core micelles for targeted drug delivery.
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Micelles, self-assembling nanosized colloidal particles with a hydrophobic core and hydrophilic shell are currently successfully used for the solubilization of various poorly soluble pharmaceuticals and demonstrate a series of attractive properties as drug carriers. Polymeric micelles, i.e. micelles
Recurrent miscarriage syndrome due to blood coagulation protein/platelet defects: prevalence, treatment and outcome results. DRW Metroplex Recurrent Miscarriage Syndrome Cooperative Group.
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Although first-time miscarriages are usually caused by chromosomal defects, about 55% of recurrent miscarriages are caused by procoagulant defects that induce thrombosis and infarction of placental vessels. Of recurrent miscarriages, about 7% are caused by chromosome defects, 15% to hormonal
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