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Side 1 fra 62 resultater
[Gamma-aminobutyric acid concentrations in the plasma in unconscious patients with severe craniocerebral trauma or nontraumatic intracranial hemorrhage].
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The detection of cerebral lesions by chemical laboratory studies has not as yet been possible. Tests were carried out to determine whether there was an increase in plasma concentration of the neurotransmitter gamma-aminobutyric acid (GABA) in 12 unconscious patients: 6 with severe craniocerebral
[The association between plasma neurotransmitters levels and depression in acute hemorrhagic stroke].
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OBJECTIVE
To explore the relation between plasma neurotransmitters (Glutamic acid, GAA; γ-aminobutyric acid, GABA; 5-hydroxytryptamine, 5-HT; and noradrenaline, NE) and depression in acute hemorrhagic stroke.
METHODS
Objectives were screened from consecutive hospitalized patients with acute stroke.
Medical therapy for intracerebral hematoma with the gamma-aminobutyric acid-A agonist muscimol.
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OBJECTIVE
No therapy has been rigorously proven effective for intracerebral hematoma, although surgery is frequently used for some types of lobar hemorrhages. Since intracerebral mass causes significant ischemia in surrounding brain, we reasoned that anti-ischemia therapy might improve outcome after
Gamma aminobutyric acid (GABA) receptor agonists for acute stroke.
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BACKGROUND
Gamma aminobutyric acid (GABA) receptor agonists have been shown to have a neuroprotectant effect in reducing infarct size and improving functional outcome in animal models of cerebral ischemia. However, the sedation effects of GABA receptor agonists have limited their wider application
Gamma aminobutyric acid (GABA) receptor agonists for acute stroke.
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BACKGROUND
Gamma aminobutyric acid (GABA) receptor agonists have been shown to have a neuroprotectant effect in reducing infarct size and improving functional outcome in animal models of cerebral ischemia. However, the sedation effects of GABA receptor agonists have limited their wider application
Hemorrhage activates catecholaminergic neurons sensitive to GABA in the nucleus of the solitary tract with ascending projections to the subfornical organ in rats.
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The activity of neurons in the region of the nucleus of the solitary tract (NTS) that were antidromically identified by electrical stimulation of the rat subfornical organ (SFO) was tested for a response to microiontophoretic application of gamma-aminobutyric acid (GABA), hemorrhage (10 ml/kg
Successful Intrathecal Baclofen Therapy for Intractable Paroxysmal Sympathetic Hyperactivity in Patient with Pontine Hemorrhage: A case report.
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Paroxysmal sympathetic hyperactivity (PSH) is characterized by increased activity of the sympathetic nervous system. Although several treatments have been proposed for PSH, their efficacies are uncertain. We report a case of a patient with intractable PSH after pontine hemorrhage who was treated
Degeneration of cholinergic rat basal forebrain neurons after experimental subarachnoid hemorrhage.
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OBJECTIVE
The reasons for neuropsychological deficits after subarachnoid hemorrhage (SAH) are fairly unknown. Cholinergic basal forebrain (BFB) neurons are essential for attention, memory, and emotion. We investigated possible changes in the cholinergic BFB and its hippocampal and neocortical
Amelioration of cerebral vasospasm and secondary injury by Vigabatrin following experimental subarachnoid hemorrhage in the rabbit
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Objective: Vigabatrin, an antiepileptic drug, increases the level of gamma aminobutyric acid in the brain via inhibiting its catabolism. As gamma aminobutyric acid has been proved to have vasodilatory effect, in the present study, we aimed to investigate the effect
[The use of a vitamin and metabolite complex for correcting the disorders in systemic and organ hemodynamics during liver resection under conditions of acute blood loss].
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The efficacy of some infusion media, vitamins, and metabolites in resection of the liver in acute blood loss was studied in experiments on dogs. Inclusion of vitamins B1, B2, and B6, lipoic acid, calcium pantothenate, nicotinamide, solution of alpha-glutamate and gamma-aminobutyric acid (aminalone)
[Effect of dahuang zhechong pill on content of amino acids in hippocampal tissue of ischemic cerebral hemorrhagic rats].
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OBJECTIVE
To observe the effect of Dahuang Zhechong Pill (DZP) on the content of amino acids in hippocampal tissue of model rats of ischemic cerebral hemorrhage (ICH).
METHODS
Collagenase and heparin were injected into caudate nucleus to establish ICH rat model. The content of glutamic acid (Glu),
Rat vasopressin cell responses to simulated hemorrhage: stimulus-dependent role for A1 noradrenergic neurons.
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c-fos expression mapping and electrophysiological recording experiments were done to clarify the role of the A1 noradrenergic cell group in the vasopressin response to hypotensive hemorrhage. In pentobarbital-anesthetized rats, moderate and severe hypotensive hemorrhages were simulated by brief
The C1 area of rostral ventrolateral medulla: a central site integrating autonomic responses to hemorrhage.
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Activation of the sympathetic neurons and release of adrenomedullary catecholamines are the principal early reflex responses to hemorrhage. These are initiated by arterial baro- and chemoreceptors, from other cardiopulmonary receptors, and by intracerebral receptors responding to ischemia. A
Glutamine depletion in patients with Crimean-Congo Hemorrhagic Fever.
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Crimean-Congo hemorrhagic fever (CCHF) is a viral disease. There is not enough knowledge about plasma amino acid levels in CCHF. Therefore, we investigated of plasma amino acids levels in patients with CCHF and the association between the levels of these amino acids and disease severity. The plasma
Gamma-aminobutyric acid (GABA) in cerebrospinal fluid.
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Levels of gamma-aminobutyric acid (GABA) in cerebrospinal fluid (CSF) were measured by radioreceptor assay (RRA) in 25 normal controls and in 121 patients with various central nervous system disorders. CSF-GABA levels could be measured down to 5 pmoles/ml reliably by this assay. In normal controls,
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