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Reoperation for prosthetic valve degeneration after Konno aortoventriculoplasty.
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Since the introduction of the aortoventriculoplasty procedure by Konno in 1975, 16 patients have undergone aortic root augmentation by this method at the Woodruff Medical Center of Emory University. In four patients bioprosthetic valve degeneration 2 to 5 years after the Konno procedure has
Xeroderma Pigmentosum
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Xeroderma pigmentosum (XP) is a rare autosomal recessive genodermatosis that results due to mutations in nucleotide excision repair. The condition characteristically demonstrates severe photosensitivity, skin pigmentary changes, malignant tumor development, and occasionally progressive neurologic
Focal vulvitis: a psychosexual problem for which surgery is not the answer.
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In the last decade focal vulvitis has been identified as a distinct syndrome, characterized by unexplained burning vulvar pain and superficial dyspareunia. A 'Woodruff perineoplasty' has been recommended as a treatment method. A research project was conducted, investigating the long-term results of
Forty years of research on xeroderma pigmentosum at the US National Institutes of Health.
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In 1968, Dr. James Cleaver reported defective DNA repair in cultured cells from patients with xeroderma pigmentosum. This link between clinical disease and molecular pathophysiology has sparked interest in understanding not only the clinical characteristics of sun sensitivity, damage and cancer that
Shining a light on xeroderma pigmentosum.
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Xeroderma pigmentosum (XP) is a rare, autosomal recessive disorder of DNA repair characterized by sun sensitivity and UV radiation-induced skin and mucous membrane cancers. Initially described in 1874 by Moriz Kaposi in Vienna, nearly 100 years later, James Cleaver in San Francisco reported
DeSanctis-Cacchione syndrome. A case report with autopsy findings.
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One of the first patients studied by Cleaver on the DNA repair defect to ultraviolet light damage in xeroderma pigmentosum has been subjected to autopsy examination. This patient had the DeSanctis-Cacchione syndrome (microcephaly, dwarfism, mental deficiency, and choreoathetosis). Her autopsy
Acheulean technology and landscape use at Dawadmi, central Arabia.
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Despite occupying a central geographic position, investigations of hominin populations in the Arabian Peninsula during the Lower Palaeolithic period are rare. The colonization of Eurasia below 55 degrees latitude indicates the success of the genus Homo in the Early and Middle Pleistocene, but the
Clinical and necropsy findings associated with increased mortality among American alligators of Lake Griffin, Florida.
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From December, 1997, through November, 2000, 306 deaths were documented among adult and subadult American alligators (Alligator mississippiensis) of Lake Griffin, Florida (USA). Some live alligators were lethargic and unresponsive to approach. To determine the cause, we examined ten alligators
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