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Side 1 fra 159 resultater
Hypoxia-Inducible Factor-1α in Antarctic notothenioids contains a polyglutamine and glutamic acid insert that varies in length with phylogeny.
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The long evolution of the Antarctic perciform suborder of Notothenioidei in the icy, oxygen-rich waters of the Southern Ocean may have reduced selective pressure to maintain a hypoxic response. To test this hypothesis, cDNA of the key transcriptional regulator of hypoxic genes, hypoxia-inducible
Effects of succinic and glutamic acid combination on energy metabolism in the liver of mice under conditions of hypoxia.
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Treatment of mice by a combination of succinic and glutamic acids prevented the metabolic disorders in the liver under conditions of normobaric hypoxia. In addition, the activity of the mitochondrial fast metabolic cluster remained intact and lipid peroxidation was limited.
Permanent increase of immunocytochemical reactivity for gamma-aminobutyric acid (GABA), glutamic acid decarboxylase, mitochondrial enzymes, and glial fibrillary acidic protein in rat cerebral cortex damaged by early postnatal hypoxia-ischemia.
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A former study indicated that hypoxic-ischemic encephalopathy in rat sustained during early postnatal life may result in permanent epileptic activity in the baseline electroencephalogram. We, therefore, investigated whether the presumed higher firing frequency and metabolic activity of neurons in
Post-translational modification of glutamic acid decarboxylase 67 by intermittent hypoxia: evidence for the involvement of dopamine D1 receptor signaling.
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Intermittent hypoxia (IH) associated with sleep apnea leads to cardio-respiratory morbidities. Previous studies have shown that IH alters the synthesis of neurotransmitters including catecholamines and neuropeptides in brainstem regions associated with regulation of cardio-respiratory functions.
Methoxy poly (ethylene glycol)-block-poly (glutamic acid)-graft-6-(2-nitroimidazole) hexyl amine nanoparticles for potential hypoxia-responsive delivery of doxorubicin.
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Tumor microenvironment-responsive nano drug delivery vehicles are gaining mounting attention in the field of biomedical sciences. The hypoxic response of the tumorous cells due to very low partial pressure of oxygen (some time less than 2.5 mm of Hg) in the tumor tissues makes hypoxia-responsive
Hypoxia regulates the level of glutamic acid decarboxylase enzymes and interrupts inhibitory synapse stability in primary cultured neurons.
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Gamma-aminobutyric acid (GABA) is the main neurotransmitter of inhibitory synaptic transmission, which is critical for oscillatory activity and synchronization of neurons in neural networks. GABA is synthesized by glutamic acid decarboxylase (GAD) enzymes in the inhibitory neuron and, thus, the
[The effect of glutamic acid on respiration and oxidative phosphorylation in liver mitochondria under normal conditions and in hypoxia].
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[Change in the proteolytic activity of the thyroid gland following administration of glutamic acid in normal conditions and in hypoxia].
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[The effect of glutamic acid on the activity of oxidative enzymes in the heart mitochondria in hypoxia].
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[Changes in thyroid gland function under the effects of glutamic acid under normal conditions and in hypoxia].
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[Effect of hypoxia and glutamic acid on the keto acid content in the myocardium and kidneys of rats].
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[Effect of introducing glutamic acid on its content in rat tissues in the normal state and in hypoxia].
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[Effect of hypoxia on oxidative phosphorylation and glutamic acid metabolism in guinea pig's cerebellum].
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Effect of acute anoxia on the glutamic oxalacetic transaminase content of the myocardium of the rat.
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[Effect of glutamic acid on certain metabolic processes in states of hypoxia and during physical activity].
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