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Breast cancer: the great new concern.

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["The great misery" of breast cancer (author's transl)].

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Great expectations: historical perspectives on genetic breast cancer testing.

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Women who test positive for a genetic breast cancer marker may have more than a 50% chance of developing the disease. Although past screening technologies have sought to identify actual breast cancers, as opposed to predisposition, the history of screening may help predict the societal response to

Metastatic breast cancer presented as great toenail pyogenic granuloma

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Survey of treatment of primary breast cancer in Great Britain.

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A postal survey of current management of breast cancer among surgeons in Great Britain was carried out. The results showed that there is no consensus among surgeons about the treatment of primary breast cancer. Many different types of primary surgery are practised, and patterns of referral for

Survey of treatment of primary breast cancer in Great Britain.

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Primary Immunoprevention: The Great Unmet Need for Controlling Breast Cancer.

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The Breast Cancer Research Stamp: sticking with a great idea.

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Two good choices to prevent breast cancer: great taste, less filling.

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An important report in this issue of the journal by Vogel et al. (beginning on p. 696) discloses long-term follow-up data of the Study of Tamoxifen and Raloxifene (STAR) showing persisting strong effects of both drugs in preventing invasive and noninvasive breast cancer after drugs were stopped in

Protocols based on steroid receptors: Great Britain.

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Steroid receptors appear to have prognostic significance in operable and disseminated breast cancer, but not in primary locally advanced disease. Information on receptor status gives some indication of the pattern of metastatic disease. Absence of ER and PgR detect effectively patients who will not

Aromatase inhibitors in premenopause: Great expectations fulfilled?

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Tamoxifen and GnRH analogues (GnRHa) represent the mainstay of endocrine manipulations in premenopausal women. The estrogen blockade obtained by aromatase inhibitors (AIs) plus GnRHa suppresses circulating estrogens more deeply than tamoxifen plus GnRHa. Retrospective and prospective evidence

Biomarkers in the management of breast cancer: great expectations, hard times.

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Progress in biomarkers research has resulted in increasing awareness of the heterogeneity of breast cancer. The identification of subtypes with different clinical behavior and the possibility of using targeted therapy in specific subgroup of patients (eg, those with tumors overexpressing HER2) raise

Breast Cancer Metastasis Masquerading as the Great Masquerader: Sebaceous Cell Carcinoma.

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OBJECTIVE We describe the case of a patient with metastatic breast cancer who presented with eyelid margin thickening and madarosis more suggestive of sebaceous cell carcinoma than metastatic disease. Histopathology confirmed metastatic breast adenocarcinoma. METHODS A 59-year-old woman with a known

[Pay great attention to early diagnosis and treatment of breast cancer].

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[Evaluation of early detection of breast cancer in Great Britain (author's transl)].

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A large-scale trial of methods of early detection of breast cancer has been started in Great Britain. This non-randomized trial aims to compare breast cancer mortality over several years among women aged 45-64 years who have been offered various services for early detection of breast cancer. A
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