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Value of heartburn for diagnosing gastroesophageal reflux disease in severely obese patients.

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OBJECTIVE To evaluate the prevalence of gastroesophageal reflux disease (GERD) in severely obese patients and the association between symptoms and objective data of GERD in this population. METHODS A total of 158 consecutive severely obese patients (BMI > or = 40 kg/m(2)) were prospectively

Heartburn during sleep: a clinical marker of gastro-oesophageal reflux disease in morbidly obese patients.

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Gastro-oesophageal reflux disease (GORD) and morbid obesity are entities with increasing prevalence. New clinical strategies are cornerstones for their management. The aim of this study was to assess the prevalence of heartburn during sleep (HDS) and whether this symptom predicts the presence of

Comparison of objective outcomes following laparoscopic Nissen fundoplication versus laparoscopic gastric bypass in the morbidly obese with heartburn.

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BACKGROUND Heartburn and gastroesophageal reflux disease (GERD) affects approximately 25-50% of morbidly obese patients. Although objective physiologic testing has been reported extensively in patients following Nissen fundoplication, there are no previous reports of such testing in morbidly obese

Prevalence of epigastric pain, heartburn and acid regurgitation in adolescents and their parents: evidence for intergenerational association.

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OBJECTIVE Little is known of the epidemiology of upper gastrointestinal symptoms in adolescents. We examined the prevalence of, and the risk factors for, epigastric pain, heartburn and acid regurgitation in adolescents from Northern Ireland. METHODS A total of 1133 adolescents aged 12-18 years

Heartburn and other related symptoms are independent of body mass index in irritable bowel syndrome.

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BACKGROUND increasing body mass index (BMI) is a risk factor for GERD but little is known about this association in the irritable bowel syndrome (IBS). OBJECTIVE to determine the presence of heartburn and other related symptoms in relation with BMI in IBS. METHODS volunteers (n = 483) answered the

Clinical trial: factors associated with freedom from relapse of heartburn in patients with healed reflux oesophagitis--results from the maintenance phase of the EXPO study.

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BACKGROUND Ability to predict freedom from heartburn relapse during maintenance therapy for healed reflux oesophagitis may facilitate optimal treatment choices for individual patients. OBJECTIVE To determine factors predicting freedom from heartburn relapse during maintenance proton pump inhibitor

Association of symptoms of type 2 diabetic patients with severity of disease, obesity, and blood pressure.

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OBJECTIVE The symptoms of 430 type 2 diabetic patients were determined by a self-administered questionnaire before entry into the U.K. Prospective Diabetes Study. METHODS Entry into the trial followed 2 months of dietary treatment for newly diagnosed patients with type 2 diabetes. Forty symptoms

Obesity is not a contraindication to laparoscopic Nissen fundoplication.

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Obesity has been shown to be a significant predisposing factor for gastroesophageal reflux disease (GERD). However, obesity is also thought to be a contraindication to antireflux surgery. This study was undertaken to determine if clinical outcomes after laparoscopic Nissen fundoplications are

Oral neuromuscular training relieves hernia-related dysphagia and GERD symptoms as effectively in obese as in non-obese patients.

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Many physicians insist patients lose weight before their hiatal hernia (HH) condition and related symptoms including intermittent esophageal dysphagia (IED) and gastroesophageal reflux disease (GERD) can be treated, but it is not proven that body mass index (BMI) has an impact on

Use of endoluminal antireflux therapies for obese patients with GERD.

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BACKGROUND Obese patients with gastroesophageal reflux disease (GERD) refractory to medical therapy are a challenging patient population as obesity is a preoperative predictor of failure after antireflux surgery. We therefore sought to evaluate outcomes using one of two commercially available

Does massive obesity promote abnormal gastroesophageal reflux?

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Fifty consecutive massively obese patients referred for gastroplasty operations were prospectively studied to determine the existence of gastroesophageal reflux disease by means of a standardized questionnaire, 24-hr ambulatory pH-metry, and endoscopy (27 females, mean age 48 years, range 38-57

Obesity correlates with gastroesophageal reflux.

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Thirty morbidly obese patients presenting for bariatric surgery were evaluated for symptomatic and objective evidence of gastroesophageal reflux. Sixteen patients had heartburn while 14 were asymptomatic. All underwent esophageal function testing; manometry was performed in all patients, pH

Manometric abnormalities and gastroesophageal reflux disease in the morbidly obese.

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BACKGROUND Obesity is an epidemic in the USA. Many disorders are associated with obesity including gastroesophageal reflux disease (GERD). However, the prevalence of GERD and esophageal motility disorders in the morbidly obese population is unclear. METHODS During evaluation for bariatric surgery,

Gastrointestinal symptoms negatively impact on sleep quality among obese individuals: a population-based study.

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BACKGROUND Reduced sleep quality has been linked to obesity; however, no studies have assessed the impact of gastrointestinal (GI) symptoms on sleep quality among obese individuals. This study aims to determine the role of gastrointestinal symptoms on sleep among obese individuals in a

Relationship between obesity and gastroesophageal reflux disease as recorded by 3-hour esophageal pH monitoring.

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OBJECTIVE To evaluate the presence of gastroesophageal reflux disease (GERD) in a Greek cohort in relationship to the body mass index (BMI), using the 3-hr postprandial esophageal pH monitoring. METHODS Sixty-four consecutive patients (55 males, 9 females; mean age 40.7 +/- 13.7 years) with at least

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