heartburn/kræft

Esophageal adenocarcinoma (EAC) is a rare disease which is much more common in men than in women. For any given age, women with gastroesophageal reflux disease (GERD) symptoms actually have a lower risk of EAC than men without GERD symptoms. The cause of the difference in incidence rates between men

Gastroesophageal reflux disease: From heartburn to cancer.

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About 10%-15% of patients with gastroesophageal reflux disease develop Barrett's esophagus. This is considered a premalignant condition because it can progress from metaplasia to high-grade dysplasia, and eventually to adenocarcinoma. Recently, major advances have been made in the endoscopic

Life quality of postsurgical patients with colorectal cancer after supplemented diet with agaricus sylvaticus fungus.

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BACKGROUND Therapeutical alternatives, directed to improve life quality and reduce adverse effects of cancer treatment, have been the purpose of studies that try to prove the immunomodulator efficacy of medicinal fungi as coadjuvant for conventional therapies. OBJECTIVE The objective of this study

Long-term functional outcomes of laparoscopic resection for gastric gastrointestinal stromal tumors.

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BACKGROUND Laparoscopic resection is rapidly becoming the treatment of choice for small- to medium-sized gastric gastrointestinal stromal tumors (GIST). While long-term oncologic data are available, quality of life outcomes are less known. METHODS Our IRB-approved prospectively maintained database

Preliminary analysis of hybrid laparoscopic procedure for resection of gastric submucosal tumors.

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OBJECTIVE to evaluate the feasibility, safety and benefits of minimally invasive surgery for resection of gastric submucosal tumor (GSMT). METHODS we conducted a retrospective study of medical records of patients undergoing endoscopy-assisted laparoscopic resection of gastric submucosal tumors

Phase I clinical trial of oral COL-3, a matrix metalloproteinase inhibitor, in patients with refractory metastatic cancer.

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OBJECTIVE This phase I clinical trial was designed to determine the maximum-tolerated dose and dose-limiting toxicities of the matrix metalloproteinase (MMP) inhibitor COL-3 in patients with refractory solid tumors. METHODS Thirty-five patients with different cancer types were enrolled. COL-3 doses

A case of oesophageal cancer with low back pain: the accidental finding of skeletal muscle metastasis.

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Skeletal muscle metastasis is a very rare event in patients with oesophageal cancer. We herein report and discuss a case of a 65 years old man with history of gastro-esophageal reflux disease referred to our department for pyrosis associated to persistent low back pain. Oesophageal endoscopy and

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