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Indole derivatives as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders
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TECHNICAL FIELD
This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain indole derivatives and their salts and solvates.
Indole derivatives as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders
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TECHNICAL FIELD
This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain indole derivatives and their salts and solvates.
Indole derivatives as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders
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TECHNICAL FIELD
This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain indole derivatives and their salts and solvates.
Non-imidazole tertiary amines as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders
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TECHNICAL FIELD
This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain non-imidazole tertiary amine derivatives and
Histamine H3 receptor agents, preparation and therapeutic uses
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FIELD OF THE INVENTION
The present invention relates to novel biaryl compounds, and to the use of these compounds as pharmaceutical compositions, to pharmaceutical compositions comprising the compounds, to methods of treatment employing these compounds and compositions, and to intermediates and
Histamine H3 receptor agents, preparation and therapeutic uses
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The present invention relates to novel benzyl ether compounds, as well as intermediates and methods for preparing such compounds, and to the use of these compounds as pharmaceutical compositions, and to pharmaceutical compositions comprising the compounds, and to methods of treatment employing these
Histamine H3 receptor agents, preparation and therapeutic uses
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The present invention relates to novel heteroaromatic aryl compounds, and to the use of these compounds as pharmaceutical compositions, to pharmaceutical compositions comprising the compounds, to methods of treatment employing these compounds and compositions, and to intermediates and methods for
Histamine H3 receptor agents, preparation and therapeutic uses
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FIELD OF THE INVENTION
The present invention relates to novel biaryl compounds, and to the use of these compounds as pharmaceutical compositions, to pharmaceutical compositions comprising the compounds, to methods of treatment employing these compounds and compositions, and to intermediates and
Histamine H3 receptor agents, preparation and therapeutic uses
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The present invention relates to novel aryl-methanone-pyrrolidinyl-methyl-pyrrolidinyl compounds, to pharmaceutical compositions comprising the compounds, to methods of treatment employing these compounds and compositions, and to intermediates and methods for making these compounds.
The histamine H3
Histamine H3 receptor agents, preparation and therapeutic uses
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The present invention relates to novel substituted aryl-methanone-pyrrolidinyl-methyl-pyrrolidinyl compounds, and to the use of these compounds as pharmaceutical compositions, to pharmaceutical compositions comprising the compounds, to methods of treatment employing these compounds and compositions,
Pyrrolidine derivatives as histamine H3 receptor antagonists
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The present invention relates to novel substituted phenyl-methanone-pyrrolidinyl-methyl-pyrrolidinyl compounds, and to the use of these compounds as pharmaceutical compositions, to pharmaceutical compositions comprising the compounds, to methods of treatment employing these compounds and
Histamine H3 receptor antagonists, preparation and therapeutic uses
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The present invention relates to histamine H3 receptor antagonists, and as such are useful in the treatment of disorders responsive to the inactivation of histamine H3 receptors, such as obesity, cognitive disorders, attention deficit disorders, and the like.
The histamine H3 receptor (H3R) is a
Histamine H3 receptor inhibitors, preparation and therapeutic uses
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The present invention relates to novel heteroaromatic aryl compounds, and to the use of these compounds as pharmaceutical compositions, to pharmaceutical compositions comprising the compounds, to methods of treatment employing these compounds and compositions, and to intermediates and methods for
Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses
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BACKGROUND OF THE INVENTION
The present invention relates to histamine H3 receptor antagonists, and as such are useful in the treatment of disorders responsive to the inactivation of histamine H3 receptors, such as obesity, cognitive disorders, attention deficient disorders and the like.
The
Heterocyclyl compounds as histamine H.sub.3 receptor ligands
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RELATED APPLICATIONS
This application is a 35 U.S.C. .sctn.371 national stage filing of International Application No. PCT/IN2010/000740, filed Nov. 15, 2010, which claims priority under 35 U.S.C. .sctn.365 to India Patent Application Serial No. 2551/CHE/2010, filed Sep. 2, 2010. The entire contents
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