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lipoxygenase/infarkt
Linket gemmes på udklipsholderen
10 resultater
Use of 5-lipoxygenase activating protein (FLAP) gene to assess susceptibility for myocardial infarction
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BACKGROUND OF THE INVENTION
Myocardial infarction (MI) is one of the most common diagnoses in hospitalized patients in industrialized countries. Myocardial Infarction generally occurs when there is an abrupt decrease in coronary blood flow following a thrombotic occlusion of a coronary artery
Lipoxygenase inhibiting 1-arylalkyl-, 1-arylthio-, and 1-aryloxypyrazole-4,5-diones
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The invention relates to pyrazoledione derivatives, processes for their preparation, their use in the prophylaxis and therapy of diseases of the respiratory tract, inflammations, rheumatism, thromboembolic diseases, ischaemias and infarcts, cardiac arrhythmias and arteriosclerosis, and mixtures of
Bis-S-alkylbenzene derivatives
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FIELD OF THE INVENTION
This invention relates to novel bis-S-alkylbenzene derivatives which exert an inhibition effect on lipoxygenase, in particular, 5-lipoxygenase, and to a lipoxygenase inhibitor composition containing the same.
BACKGROUND OF THE INVENTION
5-lipoxygenase is an enzyme involved in
Substituted chromans and their use in the treatment of asthma, arthritis and related diseases
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BACKGROUND OF THE INVENTION
The present invention is directed to substituted chromans of the formula (I), depicted below, which by inhibiting 5-lipoxygenase enzyme are useful in the prevention or treatment of asthma, arthritis, psoriasis, ulcers, myocardial infarction, stroke and related disease
Substituted tetralins, chromans and related compounds in the treatment and related compounds in the treatment of asthma, arthritis and related diseases
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BACKGROUND OF THE INVENTION
The present intention is directed to substituted tetralins, chromans and related compounds of the formula (I), depicted below, which by inhibiting 5-lipoxygenase enzyme and/or blocking leukotriene receptors, are useful in the prevention or treatment of asthma, arthritis,
Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases
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BACKGROUND OF THE INVENTION
The present invention is directed to substituted tetralins, chromans and related compounds of the formula (I), depicted below, which by inhibiting 5-lipoxygenase enzyme and/or blocking leukotriene receptors, are useful in the prevention or treatment of asthma, arthritis,
Substituted tetralins, chromans and related compounds in the treatment of asthma
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BACKGROUND OF THE INVENTION
The present invention is directed to substituted tetralins, chromans and related compounds of the formula (I), depicted below, which by inhibiting 5-lipoxygenase enzyme and/or blocking leukotriene receptors, are useful in the prevention or treatment of asthma, arthritis,
Fused phenol derivatives
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SUMMARY
This invention is related to fused phenol derivatives.
More particularly, this invention is related to:
(1) fused phenol derivatives of the formula (I): ##STR3## wherein all the symbols are the same meaning as hereafter defined, and non-toxic salts thereof and non-toxic acid addition salts
Fused phenol derivatives
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SUMMARY
This invention is related to fused phenol derivatives.
More particularly, this invention is related to:
(1) fused phenol derivatives of the formula (I): ##STR3## wherein all the symbols are the same meaning as hereafter defined, and non-toxic salts thereof and non-toxic acid addition salts
Bis-imidazolinoamino derivatives as antiallergy compounds
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This invention relates to new chemical compounds which posses valuable therapeutic activity particularly as lipoxygenase and phospholipase C inhibitors and platelet-activating factor receptor antagonists. These compounds possess anti-inflammatory, anti-asthmatic and antiallergic properties and are
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