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Myxomatosis in domestic rabbits in Oregon.

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An epizootic of myxomatosis involved 26 rabbitries in western Oregon. Major clinical signs were inflammation and edema of the eyelids, conjunctiva, and anogenital area. Mortality ranged from 20 to 50%. On histologic examination, intracytoplasmic inclusion bodies were readily apparent in the

Histopathologic alterations associated with Anisakis larvae in Pacific herring from Oregon.

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A histopathologic study of Anisakis sp. larvae in Pacific herring (Clupea harengus pallasi) is presented. Tissue alterations included mechanical compression of the pancreas and liver, granulomatous inflammation and necrosis of the liver, and trauma to the muscularis externa of the pyloric caeca.

A retrospective histopathological survey of capillariasis in raccoons (Procyon lotor) from Oregon.

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A 2-yr retrospective survey (1995-1998) of 63 adult raccoons (Procyon lotor) from Oregon, northwestern United States, was conducted by histopathological examination of various tissues. An overall prevalence of capillariasis was recorded in 52% of the raccoons. Highest prevalence of nematodes (29/30,

Inflammatory neurological disease in patients treated with tumor necrosis factor alpha inhibitors.

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BACKGROUND TNF alpha inhibitor (TNFAI) therapy has been associated with inflammatory neurological syndromes. OBJECTIVE To present 10 new cases of TNFAI associated neurological disease and a review of the literature. METHODS The design and methods were based on case series collected from Oregon

Drug-induced ocular inflammatory diseases.

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Ocular inflammation can arise in the form of conjunctivitis, uveitis, episcleritis and scleritis. The uveitides can be subdivided by anatomical location into anterior and posterior uveitis or categorized by location of inflammation, e.g., iritis, pars planitis or iridocyclitis. Multiple drugs have

IL-33/ST2/IL-9/IL-9R signaling disrupts ocular surface barrier in allergic inflammation.

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This study was to explore a novel IL-33/ST2/IL-9/IL-9R signaling pathway that disrupts ocular surface barrier and amplifies allergic inflammation. Two murine models of experimental allergic conjunctivitis (EAC) and IL-9 topical challenge in wild type Balb/c and ST2^-/- mice, and two

Persistence of Staphylococcus aureus colonization among individuals with immune-mediated inflammatory diseases treated with TNF-α inhibitor therapy.

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OBJECTIVE We investigated the relationship between Staphylococcus aureus colonization and the use of immunosuppressive therapies in patients with immune-mediated inflammatory diseases (IMIDs). METHODS We prospectively enrolled IMID patients from the rheumatology and dermatology departments of Oregon

0.005% Preservative-Free Latanoprost Induces Dry Eye-Like Ocular Surface Damage via Promotion of Inflammation in Mice.

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UNASSIGNED To investigate the side effects of preservative-free 0.005% latanoprost on the murine ocular surface. UNASSIGNED We applied 0.005% latanoprost or vehicle in mice in two patterns for 14 to 28 days. Tear production was measured by phenol red cotton test, and corneal epithelial barrier

A role for methotrexate in the management of non-infectious orbital inflammatory disease.

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OBJECTIVE To evaluate the clinical usefulness of methotrexate for patients with non-infectious orbital inflammatory disease who fail to respond to systemic corticosteroids and/or orbital irradiation. METHODS The medical records of patients with non-infectious orbital inflammatory disease who were

Pilot study of inflammatory responses following a negative imaginal focus in persons with chronic pain: analysis by sex/gender.

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BACKGROUND Recent evidence suggests that differential stress and immune responses may play a role in the sex/gender disparity for pain. Pain pathology and psychological stress are both associated with elevated levels of proinflammatory cytokines. OBJECTIVE This pilot study tested a negative imaginal

Effect of a Nutrition Support Formula in Adults With Inflammatory Bowel Disease: A Pilot Study.

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Due to the high prevalence of nutrient deficiencies in patients with inflammatory bowel disease (IBD), routine monitoring of nutrient status and supplementation are recommended.This preliminary study was implemented to prospectively identify potential

A folate receptor-α-specific ligand that targets cancer tissue and not sites of inflammation.

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Folic acid has been frequently exploited to target attached drugs to cells that overexpress a folate receptor (FR). Unfortunately, folic acid and folate-linked drugs bind equally well to both major isoforms of the FR-that is, FR-α, which is primarily expressed on malignant cells, and FR-β, which is

Is this recently characterized gastrointestinal pathogen responsible for rising rates of inflammatory bowel disease (IBD) and IBD associated autism in Europe and the United States in the 1990s?

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In 2006, a pathogenic variant of the common intestinal organism Blastocystis was discovered in patients who were experiencing chronic gastrointestinal symptoms. Most species of Blastocystis inhabit humans with no symptoms. The discovery of a pathogenic variant of Blastocystis is significant, because

Gene Expression Profiling and Heterogeneity of Nonspecific Orbital Inflammation Affecting the Lacrimal Gland.

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UNASSIGNED Although a variety of well-characterized diseases, such as sarcoidosis and granulomatosis with polyangiitis, affect the lacrimal gland, many patients with dacryoadenitis are diagnosed as having nonspecific orbital inflammation (NSOI) on the basis of histology and systemic disease

Effect of sepsis and systemic inflammatory response syndrome on neonatal hearing screening outcomes following gentamicin exposure.

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OBJECTIVE Hearing loss in neonatal intensive care unit (NICU) graduates range from 2% to 15% compared to 0.3% in full-term births, and the etiology of this discrepancy remains unknown. The majority of NICU admissions receive potentially ototoxic aminoglycoside therapy, such as gentamicin, for

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