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pedicularis longipes/kræft

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Iridoid Derivatives from Pedicularis uliginosa Bunge and Their Cytotoxic Activity.

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Three new iridoids, (rel-4aS,7S,7aS)-1,4a,5,6,7,7a-hexahydro-7-hydroxyl-7-methyl-cyclopenta[c]pyran-4-carboxaldehyde (1), 1,3,5,6-tetrahydro-1-methoxyl-7-methyl-cyclopenta[c]pyran-4-carboxaldehyde (2), and (rel-1R,4S,4aS,7R,7aR)-7-methylhexahydro-1,4-(epoxymethano)cyclopenta[c]pyran-3(1H)-one(3),

Natural antioxidant pedicularioside G inhibits angiogenesis and tumourigenesis in vitro and in vivo.

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Pedicularioside G is a new compound of phenylpropanoid glycosides, isolated from Pedicularis striata in our laboratory. Pedicularioside G inhibited two major angiogenic responses, human umbilical vein endothelial cell proliferation and migration, as well as neovascularization in a chicken embryo

In vitro modulation of telomerase activity, telomere length and cell cycle in MKN45 cells by verbascoside.

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Screening of natural products with anti-tumor activity as telomerase inhibitor is a new subject in the field of tumor therapy. Using telomerase PCR ELISA, telomere DNA hybridization and flow cytometry analysis, the effects of verbascoside, a phenylpropanoid glucoside extracted from Pedicularis
Pedicularis longiflora Rudolph (Orobanchaceae) and Allium carolinianum Linn (Alliaceae) are two important medicinal plants found in trans-Himalayan Changthang. The immunomodulatory potential of these plants has not been explored. In the present study, we evaluated the in vitro and in vivo

Docking study of cistanoside C to telomeric DNA fragment.

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Experiments show that the natural products phenyl propanoid glycosides (PPGs) extracted from the plant Pedicularis spicata are capable of repairing DNA damaged by oxygen radicals. Based on kinetic measurements and experiments on tumor cells, a theoretical study of the interaction between PPG
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