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phoenix/hypersensitivity

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BACKGROUND Date-palm (Phoenix dactylifera L.) fruits are eaten daily by most inhabitants of the Middle East and the neighboring countries. Recent reports have indicated that dates are allergenic. This study aimed to investigate the antigenic and allergenic potential of date
The effects of oral ingestion of a hot water extract of matured fruit of the date palm tree (Phoenix dactylifera L.) on allergic responses were investigated in mite-sensitized mice. Sneezing and nose rubbing events in mice given a date extract-added diet were significantly lower than in those given

Immunological markers in allergic rhinitis patients treated with date palm immunotherapy.

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OBJECTIVE Allergic rhinitis (AR) is regulated by the local production and release of several cytokines. Allergen specific immunotherapy (IT) has been widely used for many years as a specific treatment of allergic diseases. This study aimed to investigate the changes in clinical and immunological

Sublingual Versus Subcutaneous Immunotherapy as regards Efficacy and Safety in Respiratory Allergic Patients.

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Subcutaneous immunotherapy (SCIT) is a well-established treatment modality for allergic patients that has been successfully used for many decades. Sublingual immunotherapy (SLIT) was introduced over the last 20 years as a safer alternative to SCIT with no single case of mortality has ever been

Allergy to kiwi: is component-resolved diagnosis in routine clinical practice really impossible?

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BACKGROUND Kiwi allergy is frequent and can be the result of sensitization to a number of allergens showing different physicochemical characteristics. Component-resolved diagnosis of kiwi allergy is still unavailable in routine clinical practice. OBJECTIVE To investigate whether component
BACKGROUND Date fruits are allergenic and standardized extracts are required for diagnosis and therapy of this allergy. Since there are several cultivars of dates, this study was carried out to assess the allergenicity of different cultivars in order to select suitable source material for

R848, a Toll-like receptors 7 and 8 agonist, a potential therapy for allergic rhinitis patients.

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OBJECTIVE There is a growing interest in the targeting of Toll-like receptors (TLRs) for the treatment of allergic diseases. TLRs7/8 ligands are future candidates of therapeutic value in allergic rhinitis (AR). This study focus on TLRs7/8 ligand; resiquimod (R848) as an adjuvant to immunotherapy

Allergic rhinitis in the Middle East.

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BACKGROUND Current military operations in the Middle East involve active duty, National Guard, and reserve troops from all services. Despite common misconceptions, the desert environment in this region has significant aeroallergen seasons that may exacerbate allergic rhinitis. OBJECTIVE To review
BACKGROUND Date fruit and pollen antigens share a number of cross-reactive epitopes. Date pollen has been shown to cross-react with antigens from Artemisia, cultivated rye (Secale cereale), Timothy grass (Phleum pratense), Sydney golden wattle (Acacia longifolia) and Bermuda grass (Cynodon dactylon)

The nature of melon allergy in ragweed-allergic subjects: A study of 1000 patients.

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Previous studies suggest cross-reactivity between specific ragweed pollen and melon allergens. This study was designed to clarify the origin of the cross-reactivity between ragweed pollen and the gourd family. One thousand ragweed-allergic subjects were interviewed about the presence of oral allergy

Component-resolved diagnosis of plant food allergy by SPT.

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BACKGROUND Fruits and vegetables may contain both labile and stable allergens. The former induce only OAS, whereas stable allergens may induce systemic reactions. Component-resolved diagnosis (CRD) of allergy to plant foods is therefore essential for the clinical management of allergic
BACKGROUND Date palm pollen allergy is frequently associated with polysensitisation. Observational studies have suggested that date-palm-sensitised individuals could be included in a distinct group of polysensitised patients. The objectives of the study were to analyse the clinical characteristics

Aerobiological studies and low allerginicity of date-palm pollen in the UAE.

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Date-Palm trees (Phoenix dactylifera L.) are the most abundant crop in the United Arab Emirates (UAE). The aim of this work was to conduct aerobiological studies on Date-Palm pollens and correlate that to allergenicity. An aerobiological survey was performed at three Date-Palm farms.

Identification of 2 new allergens of Phoenix dactylifera using an immunoproteomics approach.

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The date palm (Phoenix dactylifera) has a wide geographical distribution (Middle East, Mediterranean, central Africa, western Asia, Australia, and North America). Pho d 2, the major allergen of date palm pollen was recently identified as a profilin, yet little is known about the nature of the other
Pollen from ten staminate cultivars of the date palm (Phoenix dactylifera L.) were compared for their antigenic and allergenic potentials. Crude extracts from the various cultivars were tested in 6 atopic patients with confirmed allergy to date pollen in order to determine any differences or
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