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phosphatidyl choline/blødning
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13 resultater
[The effect of acute fatal blood loss on post-resuscitation changes in heart phospholipids and prevention of them].
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Acute lethal hemorrhage and resuscitation led to a decrease in content of phosphatidyl-choline, -ethanolamine, -serine and cardiolipin but increased lysophosphatidyl choline in rat heart muscle. Within the first week catabolism of phospholipids predominated, maximal rate of which was detected at the
Choline phosphate functionalized cellulose membrane: A potential hemostatic dressing based on a unique bioadhesion mechanism.
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Wound dressings are a key component in provision of optimal conditions for bleeding control and wound healing. For absorbent dressings, electrostatic interactions are frequently utilized as one of the mechanisms driving dressing adhesion. Herein, a choline phosphate functionalized biocompatible
The effect of a calcium channel antagonist, Nisoldipine, on the ischemia-induced change of canine sarcolemmal membrane.
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Ischemic injury was produced in the dog heart by occluding the left anterior descending coronary artery just below the second diagonal branch for a duration of 1.5 h followed by the release of occlusion. Nisoldipine, 3.5 micrograms/kg was injected intravenously 10 min before the occlusion and again
[Experimental study of glucocorticoid in the treatment of acute respiratory distress syndrome induced by E.coli].
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OBJECTIVE
To evaluate the effect of glucocorticoid (GC) in the treatment of septic acute respiratory distress syndrome (ARDS).
METHODS
ARDS model was reproduced by intraperitoneal injection of E.coli in piglets. Nine male piglets were randomly divided into control (C group), early (GC1) and middle
The renal phospholipid composition of choline-deficient rats.
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The base composition of the phospholipids involved in the N-methylation pathway for the biosynthesis of phosphatidyl choline was determined in normal and severely hemorrhagic rat kidneys. There was a decrease in the proportion of phosphatidyl choline and phosphatidyl ethanolamine in the renal total
Pulmonary and serum surfactant phospholipids and serum catecholamines in strangulation. An experimental study on rats.
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Elevations of phospholipid and catecholamine concentrations in the blood are regarded as the vital reactions in asphyxial deaths, which leave few or no morphological signs in the body. These vital reactions were tested here, under strict experimental conditions, employing rapid asphyxia. Rats
Studies on a new variant of the Hermansky-Pudlak syndrome: qualitative, ultrastructural, and functional abnormalities of the platelet-dense bodies associated with a phospholipase A defect.
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The structure and functions of platelets from a patient in whom albinism and hemorrhagic diathesis were associated have been investigated. Electron microscope studies showed a large reduction in the number of dense bodies and this was confirmed by an examination of fluorescent platelets loaded with
Traumatic head injury and pulmonary damage.
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Head-injury victims may develop pulmonary complications such as hemorrhagic edema, congestion, and hyperemia. In the present experiments we examined changes in lung surface tension, cholesterol, and phospholipids of alveolar lavage recovered from cats experimentally exposed to a sudden lethal blow
[Biological effect of liposomes in hypoxic conditions of various etiologies].
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The antihypoxic and antioxidative effects of phosphatidyl choline liposomes have been studied in hypoxic hypoxia, pneumonia, and acute blood loss. It was demonstrated that the body tolerance of persisting hypoxia increased on liposome administration due to elimination of lactate-acidosis, inhibition
Immunization with outer membrane proteins of Pasteurella multocida (6:B) provides protection in mice.
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The immunoprotective efficacy of Pasteurella multocida (6:B) outer membrane proteins (OMPs) was examined in the mouse model. Bacterial OMPs were extracted using sarkosyl method and analysed by sodium dodecyl sulphate-polyacrylamide gel electrophoresis and immunoblotting. Prototype vaccines were
Acceleration of epithelial cell syndecan-1 shedding by anthrax hemolytic virulence factors.
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BACKGROUND
It has been recently reported that major pathogens Staphylococcus aureus and Pseudomonas aeruginosa accelerate a normal process of cell surface syndecan-1 (Synd1) ectodomain shedding as a mechanism of host damage due to the production of shedding-inducing virulence factors. We tested if
Development and characterization of phyto-vesicles of wedelolactone for hepatoprotective activity.
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Wedelolactone is isolated from the dried leaves of Eclipta alba (L.) and reported to be effective as a potential hepatoprotective, antibacterial and anti hemorrhagic. Pharmacokinetic studies of wedelolactone reveal its poor absorption through the intestine. The objective of the present study is to
Hemostatic defect due to acquired circulating inhibitors against lipid procoagulant and factor VIII.
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An 85 year old woman was studied because of severe bleeding. Acquired inhibitors to factor VIII and to phospholipid procoagulants were demonstrated. Platelet factor 3 (Pf3) assay was prolonged with both kaolin and Russell's Viper Venom (Stypven-R). It was normal with patient's washed platelets and
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