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polygalacturonic acid/leukæmi
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3 resultater
Treatment of leukemia L1210 and P388 by arabinosylcytosine-polysaccharide conjugates.
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Conjugates of 1-beta-D-arabinofuranosylcytosine (araC) with two polysaccharides such as polygalacturonic acid (PGA) and carboxymethylated yeast beta-D-glucan (CMG) were tested for their antileukemic activity in vitro on a L1210 cell line in suspension culture, in soft agar assay and in vivo on
Purification of a trypsin-stable lectin with antiproliferative and HIV-1 reverse transcriptase inhibitory activity.
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A lectin, with a molecular mass of approximately 60 kDa and two different subunits exhibiting an N-terminal sequence manifesting considerable homology to phytohemagglutinin from Phaseolus species, was isolated from the ground bean (Vigna sesquipedalis cv ground bean). The lectin was unique in
Magnetic nanoparticle-peptide conjugates for in vitro and in vivo targeting and extraction of cancer cells.
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Magnetic cobalt spinel ferrite nanoparticles coated with biocompatible polygalacturonic acid were functionalized with ligands specific for targeting expressed EphA2 receptors on ovarian cancer cells. By using such magnetic nanoparticle-peptide conjugates, targeting and extraction of malignant cells
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