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13 resultater
Endothelial cell pavement pattern in the pulmonary trunk in rats in chronic hypoxia.
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Right ventricular hypertrophy, and by inference pulmonary arterial hypertension, were induced in female Wistar Albino rats by subjecting them to a barometric pressure of 380 mmHg for four weeks. A control group was kept at normal barometric pressure for a similar period of time. The cell boundaries
Effect of hypoxia on the proliferation of retinal microvessel endothelial cells in culture.
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BACKGROUND
To determine if hypoxia stimulates the proliferation of retinal microvessel endothelial cells in culture.
METHODS
Bovine retinal microvessel endothelial cells were cultured in normoxic (95% air, 5% CO2) and hypoxic (2% O2, 5% CO2, 93% N2) conditions. Endothelial cells were identified by
[Effect of hypoxia on the viability of rat brain astrocytes in vitro].
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OBJECTIVE
To investigate the effect of hypoxia on the viability of rat brain astrocytes in vitro and determine the optimal duration of hypoxic treatment for studying the biological behavior of the in vitro cultured cells in response to hypoxia.
METHODS
Rat astrocytes were cultured and identified by
[Experimental study on the effect of hypoxia on the expression of VEGF and TGF-beta1 of rat mandibular osteoblasts].
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OBJECTIVE
To observe the effects of cobalt chloride (CoCl2)-simulated hypoxia on VEGF and TGF-beta1 expression and to provide theoretical basis for deciphering the molecular mechanism of clinical distraction osteogenesis.
METHODS
The mandibular osteoblasts were obtained from newborn Wistar rats
Lysyl oxidase is associated with the epithelial-mesenchymal transition of gastric cancer cells in hypoxia.
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OBJECTIVE
It has been reported that lysyl oxidase (LOX) is a hypoxia-responsive factor and is associated with the malignant progression of carcinoma. The aim of this study was to clarify the relationship between the epithelial-mesenchymal transition (EMT) and LOX in gastric cancer cells under
ITE promotes hypoxia-induced transdifferentiation of human pulmonary arterial endothelial cells possibly by activating transforming growth factor-β/Smads and MAPK/ERK pathways.
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This study aimed to investigate the transdifferentiation of human pulmonary arterial endothelial cells (HPAECs) into smooth muscle like (SM-like) cells under hypoxic conditions and reveal the role of endogenous small molecular compound 2-(1'H-indole-3'-carbonyl)-thiazole-4-carboxylicacid methyl
Establishment and characterization of new cell lines of anaplastic pancreatic cancer, which is a rare malignancy: OCUP-A1 and OCUP-A2.
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BACKGROUND
Anaplastic pancreatic cancer (APC) cell lines have been scarcely established.
METHODS
The morphology, gene expressions, karyotyping and epithelial-mesenchymal transition markers of newly established APC cell lines OCUP-A1 and OCUP-A2 were analyzed. Their abilities of proliferation under
The origins of Sattler's veil.
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The symptoms of Sattler's veil accompany prolonged wear of thick contact lenses and are thought to be the result of epithelial hypoxia. We studied light scattering in the isolated rabbit cornea after hypoxia with optical techniques. We found that hypoxia produced a polygonal mesh of light
[Experimental study of the function of nuclear factor-κB-dependent epithelial to mesenchymal transition in pancreatic cancer cells under hypoxic conditions].
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OBJECTIVE
To investigate the function of nuclear factor (NF)-κB in the epithelial to mesenchymal transition induced by hypoxia in pancreatic cancer cells.
METHODS
For cultured pancreatic cancer cells (BxPC-3 and Panc-1) under hypoxic and normoxic conditions, the differences in the morphology were
[Comparative study on biological characteristics between different generations of rabbit nucleus pulposus cells].
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UNASSIGNED
To research the biological characteristics of different generations of rabbit nucleus pulposus cells (NPCs) that were cultured with natural culture and subculture method.
UNASSIGNED
The thoracolumbar segments of New Zealand white rabbits (6-8 weeks old and weighing 1.5-2.5 kg) were
Membrane structure in mammalian astrocytes: a review of freeze-fracture studies on adult, developing, reactive and cultured astrocytes.
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The application of freeze-fracture techniques to studies of brain structure has led to the recognition of two unsuspected specializations of membrane structure, each distributed in a specific pattern across the surface of astrocytes. 'Assemblies' (aggregates of uniform, small particles packed in
[Carcinomatous lymphangitis].
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BACKGROUND
Carcinomatous lymphangitis is a radioclinical entity accounting for about 8% of all cases of lung metastasis defined as the presence of tumoral cells in lymph vessels and lung interstitium.
METHODS
Biopsy specimens or bronchial brushings obtained by fibroendoscopy or bronchioalveolar
Establishment and characterization of a clear cell carcinoma cell line, designated NOCC, derived from human ovary.
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A cell line, designated NOCC, was established from the ascites of a patient with clear cell adenocarcinoma of the ovary. The cell line has been grown without interruption and continuously propagated by serial passaging (more than 76 times) over 7 years. The cells are spherical to polygonal-shaped,
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