In the present study we show the capacity of an extract of the fern Polypodium leucotomos (PLE) to partially inhibit the production of cytokines showing a Th1 pattern (IL-2, IFN-gamma and TNF-alpha) in human PHA-stimulated peripheral blood mononuclear cells. The percentage of inhibition was 24% for
Polypodium leucotomas extract is a natural product derived from a tropical fern that is available as an over-the-counter product in the United States and several other countries. A designated brand of oral Polypodium leucotomas extract has been shown in several research studies to exhibit a variety
BACKGROUND
The incidences of idiopathic photodermatoses (IP) are increasing and the available therapeutic methods are often inadequate.
OBJECTIVE
To evaluate whether, in subjects affected by IP not responding to the usual available therapies, the oral administration of an extract of Polypodium
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