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Leukocytosis and left shift associated with quinidine fever.
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Fever is a well-known side effect of quinidine therapy, but an elevated white blood cell count is considered unusual. Two patients are described who had leukocytosis or a marked left shift in the white blood cell count (or both) in association with quinidine fever. Neither patient had evidence of
[Acute iridocyclitis with fever and liver involvement during quinidine therapy].
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Acute iridocyclitis is a rare hypersensitive reaction to quinidine treatment. The third case in the literature is reported here. A woman aged 80 years developed pyrexia, anorexia, nausea, skin rash and hepatic dysfunction after treatment with quinidine for two weeks. Four weeks later, while still
The effect of fever on quinine and quinidine disposition in the rat.
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The pharmacokinetics of quinine and its diastereoisomer quinidine has been investigated in normal and febrile rats. Endotoxin-induced fever in rats resulted in an increased quinine clearance (CL) (4.49 +/- 1.45 vs 1.38 +/- 0.65 L h-1 kg-1, P less than 0.001) and volume of distribution (Vd) (42.6 +/-
Fever due to quinidine.
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Drug fever due to quinidine.
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Fever secondary to ingestion of quinidine.
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Drug fever caused by quinine and quinidine.
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Fever due to quinidine; case report and review.
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Letter: fever as a toxic reaction to quinidine.
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Fever after quinidine medication; report of a case.
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Quinidine and procainamide induced fever in the same patient.
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Drug fever of quinidine. Report of a case and review of the literature.
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Fever as a sign of quinidine toxicity; report of sensitivity in two brothers with thyroid disease.
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Efficacy of a 3-day oral regimen of a quinine-quinidine-cinchonine association (Quinimax) for treatment of falciparum malaria in Madagascar.
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In the search for an effective, safe and field-adapted alternative to chloroquine for therapy of chloroquine-resistant Plasmodium falciparum infections in Africa, a 3-d oral regimen of Quinimax (an association of quinine, quinidine and cinchonine) was evaluated in 35 individuals with P. falciparum
Quinidine hepatotoxicity. A report of a case and review of the literature.
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A case is described of presumed quinidine hepatotoxicity, characterized by the development of fever, abnormal serum transaminase values, which improved after cessation of the drug but recurred after a challenge dose, and centrizonal hepatocellular necrosis detected on liver biopsy. Morphological
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