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6 resultater
Secretory leukocyte protease inhibitor as an inhibitor of tryptase
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FIELD
This invention relates to inhibition of proteases, and more particularly, to inhibition of tryptase by secretory leukocyte protease inhibitor (SLPI).
BACKGROUND
Vasoactive intestinal peptide (VIP) is a bronchorelaxant which is absent from or present only at relatively low levels in the lungs
Peptidyl heterocyclic ketones useful as tryptase inhibitors
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FIELD OF THE INVENTION
This invention relates to a series of compounds which are peptidyl heterocyclic ketone inflammatory cell serine protease inhibitors and their compositions and methods for the prevention and treatment of a variety of immunomediated inflammatory disorders, skin
Peptidyl heterocyclic ketones useful as tryptase inhibitors
Kun registrerede brugere kan oversætte artikler
Log ind / Tilmeld
FIELD OF THE INVENTION
This invention relates to a series of compounds which are peptidyl heterocyclic ketone inflammatory cell serine protease inhibitors and their compositions and methods for the prevention and treatment of a variety of immunomediated inflammatory disorders, skin
Compositions and methods for treating mast-cell mediated conditions
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to compositions and methods effective for the prevention and treatment of mast-cell mediated inflammatory disorders. The invention includes compositions and methods effective for the prevention and treatment of inflammatory
Compositions comprising a substituted benzimidazole useful for treating immunomediated inflammatory disorders
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DESCRIPTION OF THE FIELD
Tryptase, the predominant protease secreted from human mast cells, is thought to be involved in neuropeptide processing and tissue inflammation. Tryptase concentrations are elevated in the bloodstream for several hours following anaphylaxis (Schwartz et al. (1987) N. Eng. J.
Compositions and methods for treating mast-cell mediated conditions
Kun registrerede brugere kan oversætte artikler
Log ind / Tilmeld
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to compositions and methods effective for the prevention and treatment of mast-cell mediated inflammatory disorders. The invention includes compositions and methods effective for the prevention and treatment of inflammatory
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