sapogenin/natskygge

Concomitant extraction and hydrolysis of Solanum steroidal glycoalkaloids in a two-phase system containing an aqueous mineral acid and an organic water immiscible solvent, and having a boiling point under 100(o)C, is described. It is essentially a "one-pot" process, combining direct acid hydrolysis

Steroid alkaloid and sapogenin constituents of Solanum laciniatum.

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Steroid alkaloid and sapogenin constituents of Solanum laciniatum Aiton grown in Egypt.

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Steroidal alkaloids in tissue cultures and regenerated plants of Solanum dulcamara.

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Callus and cell suspension cultures were established with shoots of the soladulcidine variety of the bittersweet Solanum dulcamara L. Plantlets were regenerated from undifferentiated callus. From mixotrophic callus as well as mixotrophic suspension cultures soladulicidine, solasodine and the

A novel glucosyltransferase involved in steroid saponin biosynthesis in Solanum aculeatissimum.

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Steroidal saponins are widely distributed in many plant species. Their diverse structures have resulted in a wide range of applications, including drug and medicine production. It has been suggested that the nature of the non-saccharide and oligosaccharide portions of the saponin molecule both

Plasmodium falciparum: effect of Solanum nudum steroids on thiol contents and beta-hematin formation in parasitized erythrocytes.

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We studied the effects on total thiols glutathione (GSH) and cysteine contents in Plasmodium falciparum in vitro when treated with four steroid derivatives and a sapogenin (Diosgenone) extracted from Solanum nudum. We also determined their capacity to inhibit beta-hematin formation. We showed that

Characterization and engineering of glycosyltransferases responsible for steroid saponin biosynthesis in Solanaceous plants.

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Solanaceous plants contain steroid saponins that have diverse biological and pharmacological activities. The structures of their sugar chains play an important role in their activities. A functional glucosyltransferase SaGT4A from Solanum aculeatissimum glucosylates both steroidal sapogenins and

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