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3 resultater
Intensification of host's immunity by squalene in sarcoma 180 bearing ICR mice.
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Effect of highly purified squalene (HP-SQ) obtained from liver of a shark, Centrophorus atromarginative Garman, on antitumor activity and host's immune response was studied in sarcoma 180 bearing female ICR mice. HP-SQ was administered intraperitoneally (i.p.) to solid tumor-bearing or healthy mice
Inhibitory effect of Greenland shark liver oil combined with squalen and arctic birch ashes on angiogenesis and L-1 sarcoma growth in Balb/c mice.
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Sharks have been claimed to be resistant to cancer and oil from their livers have been used in Scandinavian folk medicine as anti-tumor drug. Shark liver oil contains 40% or more of squalene. Fish liver oil is also rich in squalene and polyunsaturated n-3 fatty acids. The aim of this work was to
Potentiation by squalene of the cytotoxicity of anticancer agents against cultured mammalian cells and murine tumor.
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Squalene (SQ) was examined for ability to potentiate the cytotoxicity and antitumor activity of anticancer agents. The dose-response curves of cell survival of cultured HeLa or V79 cells in the presence of various anticancer agents [adriamycin (ADM), 5-fluorouracil (5-FU), bleomycin (BLM) and
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