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8 resultater
Haemodynamic effects of hyoscine-N-butylbromide in ponies.
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The haemodynamic effects of hyoscine-N-butylbromide (0.30 mg/kg, intravenously) were studied in eight adult ponies in a blinded two-period crossover experiment with repeated measures. Values for heart rate were 63%, 48% and 13% greater than control values at 1, 16 and 46 min, respectively, after
Three cases of substitution errors leading to hyoscine hydrobromide overdose.
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We report three patients with anticholinergic poisoning caused by the substitution of hyoscine hydrobromide for hyoscine butylbromide in preparations compounded by two different pharmacists. The patients took the preparations for gastrointes tinal discomfort and presented with altered mental status
The QT interval and cycle length: the influence of atropine, hyoscine and exercise.
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Twenty-seven healthy male subjects of mean age 24.3 +/- 4.0 years and mean weight 74.9 +/- 9.1 kg took part in an investigation to assess the most suitable correction for the QT interval as a function of cardiac cycle length. 547 sets of data points were generated. Atropine 0.6, 1.2 and 1.8 mg, and
Accidental Unilateral Mydriasis from Hyoscine Patch in a Care Provider.
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The hyoscine patch is effective and is frequently used in motion sickness treatment. Not uncommonly, it is used to control excessive respiratory secretions in palliative patients. Patients, healthcare workers, and caregivers who administer these may experience a benign, although worrying, mydriasis
Thoracic electrical bioimpedance measurement of cardiac output and cardiovascular responses to the induction of anaesthesia and to laryngoscopy and intubation.
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Noninvasive methods of determining cardiac output (by thoracic electrical bioimpedance) and arterial pressure (by intermittent oscillometry) were used to record minute-by-minute changes in heart rate, mean arterial pressure, stroke volume, cardiac output and systemic vascular resistance following
Interactions between reflexes evoked by distension and mucosal stimulation: electrophysiological studies of guinea-pig ileum.
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Intracellular recording methods were used to examine stereotyped reflexes evoked in the circular muscle of guinea-pig small intestine by distension or repetitive deformation of the mucosal villi, in vitro. Both stimuli evoked compound excitatory junction potentials (EJPs) on the oral side of the
Premedication determines the circulatory responses to rapid sequence induction with sufentanil for cardiac surgery.
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Thirty-three patients undergoing elective aortocoronary bypass were allocated randomly to receive morphine 0.1 mg kg-1 i.m. and either lorazepam 50 micrograms kg-1 by mouth or hyoscine 6 micrograms kg-1 i.m. before rapid sequence induction of anaesthesia with sufentanil 5 micrograms kg-1 i.v.and
Acquired pendular nystagmus: its characteristics, localising value and pathophysiology.
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Investigations were made of 16 patients with acquired pendular nystagmus and a further 32 cases reported in the literature were reviewed. Amongst our own patients two thirds had multiple sclerosis, almost one third a cerebrovascular accident or angioma and two had optic atrophy with squint. The
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