Apply fastening-mimicking diet combined with a "dispelling dampness" meal replacement. For the convenience of implementation, a cycle of 4 weeks. The first 5 days of each cycle is the calorie restriction stage (daily calorie about 800kcal). The traditional Chinese medicine with dampness effect is used as the main source of calories in this stage. The normal diet is carried out under the guidance of a professional dietitian for the next 23 days. Study for 12 weeks.

A "grain package" is used to replace the "dispelling dampness" meal replacement, and the other thing is the same as the proposal in TCM-FMD.

Carrying out normal diet under the guidance of a dietitian, for 12 weeks.

Obesity

Fastening-mimicking diet combined with a "dispelling dampness" meal replacement

Fastening-mimicking diet combined with a "grain package"

Carrying out normal diet under the guidance of a dietitian.

Normal diet

Fasting-mimicking Diet Combined With Traditional Chinese Medicine for Phlegm-dampness Type Obesity Patients

Fasting-mimicking Diet Combined With Traditional Chinese Medicine for Phlegm-dampness Type Obesity Patients(FASTAR): a Randomized Controlled Study

Measuring the fasting weight of the day at the required time point and measured by the same instrument

Yuanqi Zhao,MD

Guangdong Provincial Hospital of Chinese Medicine

Guangdong Provincial Hospital of Traditional Chinese Medicine

TCM-FMD

Effect and Safety of TCM-FMD in Phlegm-Dampness Type Overweight/Obesity Patients(EASTAR)

Effect and Safety of Fasting-Mimicking Diet Combined With a "Dispelling Dampness" Meal Replacement in Phlegm-Dampness Type Overweight/Obesity Patients: A Randomized Controlled Study(EASTAR)

Clinical Professor

40 g composed of 13 g freeze dried strawberry powder + 27 g placebo powder

40 g color and taste matched placebo powder

Cardiovascular Disease

Low Dose Strawberry Powder

High Dose Strawberry Powder

Placebo Powder

Penn State CRC

Effects of Freeze Dried Strawberry Powder Supplementation on Vascular Function and Blood Markers of Cardiovascular Risk

LDL-C values calculated using the Friedewald equation

Aortic (central) blood pressure measured using the SphygmoCor System

Peripheral blood pressure measured using the SphygmoCor System

Augmentation index measured using the SphygmoCor System

Pulse wave velocity measured using the SphygmoCor System

Total cholesterol values determined by enzymatic procedures

Triglyceride values determined using enzymatic procedures

HDL-C will be estimated according to the modified heparin-manganese procedure

Plasma concentrations of oxLDL will be measured using ELISA kits

MDA will be measured using the thiobarbituric acid reactive substances (TBARS) assay

hs-CRP will be measured by latex-enhanced immunonephelometry

Penny

Distinguished Professor of Nutrition

Penn State University

California Strawberry Commission

Dyslipidemia

25g or 50g freeze-dried strawberries reconstituted in water

Freeze-dried strawberries

Dietary fiber

Oklahoma State University

Chronic Effects of Freeze-Dried Strawberry Beverage on Cardiovascular Risk Factors

Chronic Effects of Freeze-dried Strawberry Beverage on Cardiovascular Risk Factors in Subjects With Abdominal Adiposity and Dyslipidemia.

Change in lipids and lipoproteins at screen and 12 weeks of the study

Change in serum adhesion molecules (ICAM, VCAM) at screen and 12 weeks of the study.

sweet potato/triglyceride

Fasting-mimicking Diet Combined With Traditional Chinese Medicine for Phlegm-dampness Type Obesity Patients

Effect and Safety of TCM-FMD in Phlegm-Dampness Type Overweight/Obesity Patients(EASTAR)

Effects of Freeze Dried Strawberry Powder Supplementation on Vascular Function and Blood Markers of Cardiovascular Risk

Chronic Effects of Freeze-Dried Strawberry Beverage on Cardiovascular Risk Factors

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