Three new triterpene glycosides, intercedensides A (1), B (2), and C (3), were isolated from the sea cucumber Mensamria intercedens Lampert, which is found in the South China Sea, and their structures have been elucidated by spectroscopic analysis (NMR and ESIMS) and chemical transformations.
The effect of the increased levels of cholesterol in ascites tumor cells of mouse sarcoma 37 on the cytochemical activity of 4 triterpene glycosides was studied. A definite correlation between the increase in the cholesterol level in the cells and the glycoside activity was noted. The effect
OBJECTIVE
To study the antitumor activities of the triterpene glycoside colochiroside A (CA) from the sea cucumber Colochirus anceps.
METHODS
The tests of antitumor activities in vitro and in vivo were applied to demonstrate the effect of CA.
RESULTS
The preliminary cytotoxic assay of CA exhibited
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